Tuberculosis: Cellular Understanding of Disease

Nana Mireku-Gyimah, Nana Ama Mireku-Gyimah

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

Abstract

Tuberculosis is undoubtedly a public health concern. An understanding of the cellular make-up of the disease can help in its mitigation by several ways aimed at providing new preventive and therapeutic approaches. The chapter thus deliberates on some of the cellular mechanisms involved in the pathogenesis of tuberculosis (Mechanism of Mtb-host interaction, phagocytosis and immune cells, inhibition of phagolysosome maturation, inhibition of phagolysosome acidification, inhibition of ubiquitination) as well as some forms of tuberculosis (pulmonary, miliary, spinal (Pott’s) tuberculosis, and tuberculous lymphadenitis).

Original languageEnglish
Title of host publicationTubercular Drug Delivery Systems
Subtitle of host publicationAdvances in Treatment of Infectious Diseases
PublisherSpringer International Publishing
Pages15-33
Number of pages19
ISBN (Electronic)9783031141003
ISBN (Print)9783031140990
DOIs
Publication statusPublished - 1 Jan 2023

Keywords

  • Cellular mechanisms
  • Mycobacterium tuberculosis
  • Tuberculosis

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