TY - JOUR
T1 - The Unethical Use of Paracetamol As a Food Tenderizer in Four Selected African Countries
T2 - A Major Public Health Concern?
AU - Afful, Ewurabena Y.
AU - Frimpong-Manso, Samuel
AU - Bekoe, Samuel O.
AU - Barfi, Chris O.
AU - Opuni, Kwabena F.M.
AU - Oppong, Mahmood B.
N1 - Publisher Copyright:
© 2022 Bentham Science Publishers.
PY - 2022
Y1 - 2022
N2 - Paracetamol poisoning is the commonest cause of acute liver injury. Therefore, the unethical use of paracetamol as a food tenderizer poses a threat to human health. Although this is a common practice in Ghana, Uganda, Nigeria, and Kenya, there are few or no scientific records on the use of paracetamol as a food tenderizer and its deleterious effects, thus making it difficult to regulate this practice. This review aims to fully collate and present a systematic overview of the literature on the use of paracetamol as a food tenderizer in these countries, the potentially harmful effects posed by the practice, and measures in place to curb the situation. Additionally, this review aims to reveal the scientific gaps and areas requiring more research, thus providing a reference for further research to regulate this unscrupulous practice. From our extensive review of the literature, the high cost of fuel used in cooking and longer cooking times are the main reasons for the inappropriate use of paracetamol as a food tenderizer. Also, this review concludes that little has been done to create public awareness of this unethical practice. Furthermore, few ways to monitor, control and regulate this practice have been proposed.
AB - Paracetamol poisoning is the commonest cause of acute liver injury. Therefore, the unethical use of paracetamol as a food tenderizer poses a threat to human health. Although this is a common practice in Ghana, Uganda, Nigeria, and Kenya, there are few or no scientific records on the use of paracetamol as a food tenderizer and its deleterious effects, thus making it difficult to regulate this practice. This review aims to fully collate and present a systematic overview of the literature on the use of paracetamol as a food tenderizer in these countries, the potentially harmful effects posed by the practice, and measures in place to curb the situation. Additionally, this review aims to reveal the scientific gaps and areas requiring more research, thus providing a reference for further research to regulate this unscrupulous practice. From our extensive review of the literature, the high cost of fuel used in cooking and longer cooking times are the main reasons for the inappropriate use of paracetamol as a food tenderizer. Also, this review concludes that little has been done to create public awareness of this unethical practice. Furthermore, few ways to monitor, control and regulate this practice have been proposed.
KW - Paracetamol
KW - analytical methods
KW - human health
KW - para-aminophenol
KW - tenderization
KW - toxicity
UR - http://www.scopus.com/inward/record.url?scp=85177641623&partnerID=8YFLogxK
U2 - 10.2174/2949681015666220810125820
DO - 10.2174/2949681015666220810125820
M3 - Review article
AN - SCOPUS:85177641623
SN - 2949-6810
VL - 15
SP - 159
EP - 165
JO - Drug metabolism and bioanalysis letters
JF - Drug metabolism and bioanalysis letters
IS - 3
ER -