TY - CHAP
T1 - The Role of Mitochondrial Dysfunction in Metabolic Syndrome
AU - Tagoe, Emmanuel A.
AU - Santa, Sheila A.
N1 - Publisher Copyright:
© 2024 selection and editorial matter, Seth K. Amponsah, Emmanuel K. Ofori, Yashwant V. Pathak; individual chapters, the contributors.
PY - 2023/1/1
Y1 - 2023/1/1
N2 - The mitochondrion is the cell’s “powerhouse”, providing energy to drive cellular activities. Mitochondrial dysfunction has been linked to the pathogenesis of nearly every metabolic syndrome, including obesity, dyslipidaemia, and illnesses including type 2 diabetes and cardiovascular disease. The functions of mitochondria can be disrupted by biochemical and genetic alterations, environmental pollution, and infectious agents, and this functional disruption of mitochondria has been linked with several diseases. In this chapter, we discuss the mitochondria’s function in health, the factors that contribute to metabolic syndrome, as well as the therapeutic choices that are available for the management of the many components of metabolic syndrome. In addition, we discuss the future of the treatment of metabolic syndrome.
AB - The mitochondrion is the cell’s “powerhouse”, providing energy to drive cellular activities. Mitochondrial dysfunction has been linked to the pathogenesis of nearly every metabolic syndrome, including obesity, dyslipidaemia, and illnesses including type 2 diabetes and cardiovascular disease. The functions of mitochondria can be disrupted by biochemical and genetic alterations, environmental pollution, and infectious agents, and this functional disruption of mitochondria has been linked with several diseases. In this chapter, we discuss the mitochondria’s function in health, the factors that contribute to metabolic syndrome, as well as the therapeutic choices that are available for the management of the many components of metabolic syndrome. In addition, we discuss the future of the treatment of metabolic syndrome.
UR - http://www.scopus.com/inward/record.url?scp=85180065277&partnerID=8YFLogxK
U2 - 10.1201/9781003384823-5
DO - 10.1201/9781003384823-5
M3 - Chapter
AN - SCOPUS:85180065277
SN - 9781032469676
SP - 60
EP - 85
BT - Current Trends in the Diagnosis and Management of Metabolic Disorders
PB - CRC Press
ER -
