The Oleaceae family: A source of secoiridoids with multiple biological activities

Yan Li Huang; Mahmood Brobbey Oppong; Ying Guo; Li Zhi Wang; Shi Ming Fang; Yan Ru Deng; Xiu Mei Gao

doi:10.1016/j.fitote.2019.04.010

The Oleaceae family: A source of secoiridoids with multiple biological activities

Yan Li Huang, Mahmood Brobbey Oppong, Ying Guo, Li Zhi Wang, Shi Ming Fang, Yan Ru Deng, Xiu Mei Gao

Department of Pharmaceutical Chemistry

Research output: Contribution to journal › Review article › peer-review

41 Citations (Scopus)

Abstract

In the quest to search and discover bioactive compounds from nature, terpenoids have emerged as one of the most interesting and researched classes of compounds. Secoiridoid, a type of the terpenoid, has also been extensively studied, especially their chemical structures and pharmacological effects. Oleaceae is a family of woody dicotyledonous plants with broad economic and medicinal values. This family contains a large number of flavonoids, monoterpenoids, iridoids, secoiridoids and phenylethyl alcohols, of which the secoiridoids have various biological activities. The purpose of this review is to summarize the phytochemical and pharmacological of the secoiridoids (glycosides, aglycones, derivatives and dimers) in the Oleaceae family from 1987 to 2018. This review will also serve as a reference for further studies.

Original language	English
Article number	104155
Journal	Fitoterapia
Volume	136
DOIs	https://doi.org/10.1016/j.fitote.2019.04.010
Publication status	Published - Jul 2019

Keywords

Oleaceae
Oleuropein
Pharmacological effect
Phytochemistry
Secoiridoid

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10.1016/j.fitote.2019.04.010

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title = "The Oleaceae family: A source of secoiridoids with multiple biological activities",

abstract = "In the quest to search and discover bioactive compounds from nature, terpenoids have emerged as one of the most interesting and researched classes of compounds. Secoiridoid, a type of the terpenoid, has also been extensively studied, especially their chemical structures and pharmacological effects. Oleaceae is a family of woody dicotyledonous plants with broad economic and medicinal values. This family contains a large number of flavonoids, monoterpenoids, iridoids, secoiridoids and phenylethyl alcohols, of which the secoiridoids have various biological activities. The purpose of this review is to summarize the phytochemical and pharmacological of the secoiridoids (glycosides, aglycones, derivatives and dimers) in the Oleaceae family from 1987 to 2018. This review will also serve as a reference for further studies.",

keywords = "Oleaceae, Oleuropein, Pharmacological effect, Phytochemistry, Secoiridoid",

author = "Huang, {Yan Li} and Oppong, {Mahmood Brobbey} and Ying Guo and Wang, {Li Zhi} and Fang, {Shi Ming} and Deng, {Yan Ru} and Gao, {Xiu Mei}",

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doi = "10.1016/j.fitote.2019.04.010",

language = "English",

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T2 - A source of secoiridoids with multiple biological activities

AU - Huang, Yan Li

AU - Oppong, Mahmood Brobbey

AU - Guo, Ying

AU - Wang, Li Zhi

AU - Fang, Shi Ming

AU - Deng, Yan Ru

AU - Gao, Xiu Mei

PY - 2019/7

Y1 - 2019/7

N2 - In the quest to search and discover bioactive compounds from nature, terpenoids have emerged as one of the most interesting and researched classes of compounds. Secoiridoid, a type of the terpenoid, has also been extensively studied, especially their chemical structures and pharmacological effects. Oleaceae is a family of woody dicotyledonous plants with broad economic and medicinal values. This family contains a large number of flavonoids, monoterpenoids, iridoids, secoiridoids and phenylethyl alcohols, of which the secoiridoids have various biological activities. The purpose of this review is to summarize the phytochemical and pharmacological of the secoiridoids (glycosides, aglycones, derivatives and dimers) in the Oleaceae family from 1987 to 2018. This review will also serve as a reference for further studies.

AB - In the quest to search and discover bioactive compounds from nature, terpenoids have emerged as one of the most interesting and researched classes of compounds. Secoiridoid, a type of the terpenoid, has also been extensively studied, especially their chemical structures and pharmacological effects. Oleaceae is a family of woody dicotyledonous plants with broad economic and medicinal values. This family contains a large number of flavonoids, monoterpenoids, iridoids, secoiridoids and phenylethyl alcohols, of which the secoiridoids have various biological activities. The purpose of this review is to summarize the phytochemical and pharmacological of the secoiridoids (glycosides, aglycones, derivatives and dimers) in the Oleaceae family from 1987 to 2018. This review will also serve as a reference for further studies.

KW - Oleaceae

KW - Oleuropein

KW - Pharmacological effect

KW - Phytochemistry

KW - Secoiridoid

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DO - 10.1016/j.fitote.2019.04.010

M3 - Review article

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SN - 0367-326X

VL - 136

JO - Fitoterapia

JF - Fitoterapia

M1 - 104155

ER -

The Oleaceae family: A source of secoiridoids with multiple biological activities

Abstract

Keywords

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