Sustained protection from pentavalent rotavirus vaccination during the second year of life at a large, Urban United States Pediatric Hospital

Julie A. Boom, Jacqueline E. Tate, Leila C. Sahni, Marcia A. Rench, Osbourne Quaye, Slavica Mijatovic-Rustempasic, Manish M. Patel, Carol J. Baker, Umesh D. Parashar

Research output: Contribution to journalArticlepeer-review

52 Citations (Scopus)

Abstract

Fecal specimens from children presenting to Texas Children's Hospital with acute gastroenteritis were tested for the presence of rotavirus. Children were grouped according to vaccination status, and pentavalent rotavirus vaccine effectiveness was calculated. Pentavalent rotavirus vaccine effectiveness against severe rotavirus gastroenteritis was sustained during the first 2 years of the vaccination program. Overall 3-dose effectiveness was 83% to 86%; it was 92% to 93% among children 6 to 11 months of age and 78% to 84% among children 12 months of age.

Original languageEnglish
Pages (from-to)1133-1135
Number of pages3
JournalPediatric Infectious Disease Journal
Volume29
Issue number12
DOIs
Publication statusPublished - Dec 2010
Externally publishedYes

Keywords

  • diarrhea
  • rotavirus
  • rotavirus vaccine
  • vaccine effectiveness

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