Stochastic modeling approach of infectious disease with sir epidemiological compartment model

Felix Okoe Mettle, Prince Osei Affi, Emmanuel Kojo Aidoo, Shadrack Benn

Research output: Contribution to journalArticlepeer-review

Abstract

The aim of this paper is to present a review on the stochastic version of the deterministic SIR (Suscep-tible – Infectious-Recovery) epidemiological compartment model through the branching process approximation. The stochastic process (branching process) approximation was developed using the Continuous Time Markov Chains where the time variable is continuous and the state variable is discrete. The state random variables are the compartments: S(t), I(t) and R(t). In this review two ways of estimating the state transition probability has been provided and some stochastic thresholds of the branching process (basic reproduction number, Malthusian parameter and the average number of infections produced by an infectious individual in a single generation) have also been deduced. Finally, the probability of major and minor outbreak of the branching process (epidemic process) has been presented. The theoretical methods have also been validated with some examples of numerical simulations.

Original languageEnglish
Article number55
Pages (from-to)1-18
Number of pages18
JournalCommunications in Mathematical Biology and Neuroscience
Volume2020
DOIs
Publication statusPublished - 2020

Keywords

  • Branching process
  • Continuous time Markov chains
  • Maximum likelihood estimation
  • SIR model

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