Abstract
A biomarker is a molecule that can be quantified objectively, methodically, and accurately in a biological specimen. Its levels can be utilized to diagnose, evaluate illness severity, stratify risk, forecast, and inform therapeutic decisions, as well as direct treatments and their reactions. Innovative renal biomarkers in clinical practice are crucial, as they can facilitate early identification and improve kidney disease outcomes. The numerous mechanisms involved in the genesis and progression of kidney disease necessitate a collection of markers rather than a single marker to accurately reflect all changes occurring during the disease. Conventional markers may likely be replaced by new ones in the future. This review will examine the essential properties of a renal biomarker and the methods to ascertain its efficacy. We will also evaluate the clinical significance and future directions of these kidney biomarkers.
| Original language | English |
|---|---|
| Title of host publication | RENAL FAILURE |
| Subtitle of host publication | Insights from Nephrotic Syndrome to Systemic Renal Dynamics |
| Publisher | Elsevier |
| Pages | 17-36 |
| Number of pages | 20 |
| ISBN (Electronic) | 9780443330902 |
| ISBN (Print) | 9780443330919 |
| DOIs | |
| Publication status | Published - 1 Jan 2025 |
Keywords
- Renal function
- diagnostic procedure
- kidney disease
- novel biomarker
- novel therapy
- precision medicine
- renal physiology