Realities of paediatric pharmacotherapy in the developing world

Kalle Hoppu, Shalini Sri Ranganathan, Alex N.O. Dodoo

Research output: Contribution to journalReview articlepeer-review

20 Citations (Scopus)

Abstract

Diseases causing high mortality in children under 5 years of age in resource limited settings (RLS) could be treated if children in these countries had access to existing medicines. It took 30 years before the WHO Essential Medicines List (EML) considered the issue of medicines for children, with the first EML for children being published in 2007. Recent data indicate that less than half of the key paediatric essential medicines are available in countries of sub-Saharan Africa. Problems include substandard medicines, irrational use of medicines, inefficiency and even possible corruption in pharmaceutical management systems. These are global issues which affect RLS most. Clinical trials in developing countries for the benefit of children are needed but challenging in several ways. In this review, the authors will consider the following areas where progress could improve paediatric pharmacotherapy in RLS: registration and regulation of medicines, rational use of medicines, clinical trials in children and restriction of corruption in pharmaceutical management systems.

Original languageEnglish
Pages (from-to)764-768
Number of pages5
JournalArchives of Disease in Childhood
Volume96
Issue number8
DOIs
Publication statusPublished - Aug 2011

Fingerprint

Dive into the research topics of 'Realities of paediatric pharmacotherapy in the developing world'. Together they form a unique fingerprint.

Cite this