TY - JOUR
T1 - Quality of Life after Mastectomy with or without Breast Reconstruction and Breast-Conserving Surgery in Breast Cancer Survivors
T2 - A Cross-Sectional Study at a Tertiary Hospital in Ghana
AU - Nsaful, Josephine
AU - Nartey, Edmund Tetteh
AU - Dedey, Florence
AU - Bediako-Bowan, Antoinette
AU - Appiah-Danquah, Rita
AU - Darko, Kwame
AU - Ankrah, Levi Nii Ayi
AU - Akli-Nartey, Cynthia
AU - Annan, Jessie Yaoteokor
AU - Dei-Asamoa, Jessica
AU - Ahene-Amanquanor, George Amanquanor
AU - Clegg-Lamptey, Joe Nat
N1 - Publisher Copyright:
© 2024 by the authors.
PY - 2024/6
Y1 - 2024/6
N2 - (1) Background: Breast cancer is the leading malignancy worldwide, and in Ghana, it has a poor overall survival rate. However, approximately 50% of cases are cases of early-stage disease, and with advances in breast cancer treatment and improvements in survival, quality of life (QOL) is becoming as important as the treatment of the disease. (2) Methodology: This was a cross-sectional study of survivors who had breast-conserving surgery (BCS), mastectomy only (M) and mastectomy with breast reconstruction (BRS) from 2016 to 2020 at a tertiary hospital in Ghana, comparatively assessing their QOL using EORTC QLQ C-30 and EORTC QLQ BR-23. (3) Results: The study participants had an overall global health status (GHS) median score of 83.3 [IQR: 66.7–91.7] with no significant differences between the surgery types. The BRS group had statistically significant lower median scores for the functional scale (82.8 and 51.0) and the highest scores for the symptomatic scale (15.7 and 16.5). Body image was significantly lowest for the BRS group (83.3) [68.8–91.7] and highest (100) [91.7–100] for the BCS group (p < 0.001). (4) Conclusion: There is a need to develop support systems tailored at improving the QOL of breast cancer survivors taking into consideration the type of surgery performed.
AB - (1) Background: Breast cancer is the leading malignancy worldwide, and in Ghana, it has a poor overall survival rate. However, approximately 50% of cases are cases of early-stage disease, and with advances in breast cancer treatment and improvements in survival, quality of life (QOL) is becoming as important as the treatment of the disease. (2) Methodology: This was a cross-sectional study of survivors who had breast-conserving surgery (BCS), mastectomy only (M) and mastectomy with breast reconstruction (BRS) from 2016 to 2020 at a tertiary hospital in Ghana, comparatively assessing their QOL using EORTC QLQ C-30 and EORTC QLQ BR-23. (3) Results: The study participants had an overall global health status (GHS) median score of 83.3 [IQR: 66.7–91.7] with no significant differences between the surgery types. The BRS group had statistically significant lower median scores for the functional scale (82.8 and 51.0) and the highest scores for the symptomatic scale (15.7 and 16.5). Body image was significantly lowest for the BRS group (83.3) [68.8–91.7] and highest (100) [91.7–100] for the BCS group (p < 0.001). (4) Conclusion: There is a need to develop support systems tailored at improving the QOL of breast cancer survivors taking into consideration the type of surgery performed.
KW - EORTC QLQ
KW - breast cancer
KW - breast conservation
KW - breast reconstruction
KW - mastectomy
KW - quality of life
UR - http://www.scopus.com/inward/record.url?scp=85197041697&partnerID=8YFLogxK
U2 - 10.3390/curroncol31060224
DO - 10.3390/curroncol31060224
M3 - Article
C2 - 38920708
AN - SCOPUS:85197041697
SN - 1718-7729
VL - 31
SP - 2952
EP - 2962
JO - Current Oncology
JF - Current Oncology
IS - 6
ER -