Primary Isolation of Mycobacterium ulcerans

Dorothy Yeboah-Manu, Adwoa Asante-Poku, Sammy Yaw Aboagye

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

1 Citation (Scopus)

Abstract

Primary isolation of Mycobacterium ulcerans is the separation and growth of the bacterium from a mixed population either in clinical specimen or environmental specimen in pure cultures. It is a crucial activity as it can be used to monitor antimicrobial treatment, surveillance for antimicrobial resistance, and molecular epidemiology studies toward understanding pathogen ecology and transmission as well as pathogen biology. The process involves removal of unwanted fast-growing bacteria using 5% oxalic acid, inoculation on Lowenstein-Jensen medium supplemented with glycerol, and incubation at temperatures between 30 °C and 33 °C.

Original languageEnglish
Title of host publicationMethods in Molecular Biology
PublisherHumana Press Inc.
Pages17-28
Number of pages12
DOIs
Publication statusPublished - 2022

Publication series

NameMethods in Molecular Biology
Volume2387
ISSN (Print)1064-3745
ISSN (Electronic)1940-6029

Keywords

  • Clinical and environmental specimen
  • Decontamination
  • Mycobacterium ulcerans

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