TY - JOUR
T1 - Prevalence of intestinal parasites among HIV/AIDS patients attending Infectious Disease Hospital Kano, Nigeria
AU - Feyisayo Jegede, Ebenezer
AU - Ibijoke Oyeyi, Esther Tinuade
AU - Hamisu Bichi, Armayau
AU - Akwen Mbah, Henry
AU - Torpey, Kwasi
PY - 2014
Y1 - 2014
N2 - Introduction: Intestinal parasitic infection has been a major source of morbidity in tropical countries especially among HIV patients. The aim of this study was to determine prevalence of intestinal parasites and its association with immunological status and risk factors among HIV infected patients in Kano, Nigeria. Methods: 105 HIV+ subjects and 50 HIV- controls were recruited into the studies from June to December 2010. Clinical information was collected using a questionnaire. Single stool and venous blood samples were collected from each subject. Stool examination and CD4+ count were performed. Results: Prevalence of intestinal parasites was 11.4% and 6% among the HIV+ and control subjects respectively with no statistically significant difference (p=0.389). Specifically, the following intestinal parasites were isolated from HIV+ subjects: Entamoebahistolytica (5.7%), hookworm (3.8%), Entamoeba coli (1%), Blastocystishominis (1%). Only Entamoebahistolytica was isolated among the control subjects. The mean CD4+ count of HIV+ and control subjects was 287 cells/ul and 691 cells/μlrespectively while the median was 279(Q1-120, Q3-384) cell/μl and 691(Q1-466, Q3-852) cell/μlrespectively with statistically significant difference (P= 0.021).Diarrhea and the absence of anti-parasitic therapy seem to be important risk factors associated with the occurrence of intestinal parasites among HIV+ subjects. A higher prevalence (14.5%) of intestinal parasites was observed in subject with CD4+ count <350cell/μl compared to (4%) prevalence in those with CD4+ count >350cell/μl.
AB - Introduction: Intestinal parasitic infection has been a major source of morbidity in tropical countries especially among HIV patients. The aim of this study was to determine prevalence of intestinal parasites and its association with immunological status and risk factors among HIV infected patients in Kano, Nigeria. Methods: 105 HIV+ subjects and 50 HIV- controls were recruited into the studies from June to December 2010. Clinical information was collected using a questionnaire. Single stool and venous blood samples were collected from each subject. Stool examination and CD4+ count were performed. Results: Prevalence of intestinal parasites was 11.4% and 6% among the HIV+ and control subjects respectively with no statistically significant difference (p=0.389). Specifically, the following intestinal parasites were isolated from HIV+ subjects: Entamoebahistolytica (5.7%), hookworm (3.8%), Entamoeba coli (1%), Blastocystishominis (1%). Only Entamoebahistolytica was isolated among the control subjects. The mean CD4+ count of HIV+ and control subjects was 287 cells/ul and 691 cells/μlrespectively while the median was 279(Q1-120, Q3-384) cell/μl and 691(Q1-466, Q3-852) cell/μlrespectively with statistically significant difference (P= 0.021).Diarrhea and the absence of anti-parasitic therapy seem to be important risk factors associated with the occurrence of intestinal parasites among HIV+ subjects. A higher prevalence (14.5%) of intestinal parasites was observed in subject with CD4+ count <350cell/μl compared to (4%) prevalence in those with CD4+ count >350cell/μl.
KW - HIV/AIDS
KW - Intestinal parasites
UR - http://www.scopus.com/inward/record.url?scp=84898832786&partnerID=8YFLogxK
U2 - 10.11604/pamj.2014.17.295.3707
DO - 10.11604/pamj.2014.17.295.3707
M3 - Article
C2 - 25328591
AN - SCOPUS:84898832786
SN - 1937-8688
VL - 17
JO - Pan African Medical Journal
JF - Pan African Medical Journal
M1 - 295
ER -