TY - JOUR
T1 - Predictors of glycemic control, quality of life and diabetes self-management of patients with diabetes mellitus at a tertiary hospital in Ghana
AU - Gyan, Kwadwo Faka
AU - Agyenim-Boateng, Enoch
AU - Hutton-Mensah, Kojo Awotwi
AU - Opare-Addo, Priscilla Abrafi
AU - Gyabaah, Solomon
AU - Ofori, Emmanuel
AU - Asamoah, Osei Yaw
AU - Naabo, Mohammed Najeeb
AU - Owiredu, Michael Asiedu
AU - Tannor, Elliot Koranteng
N1 - Publisher Copyright:
© 2025 Gyan et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
PY - 2025/7
Y1 - 2025/7
N2 - Background The burden of diabetes mellitus (DM) in Sub-Saharan Africa is high and continues to increase. Effective DM management focuses on key goals such as glycemic control, prevention of complications and improvement of quality of life (QOL). This study therefore assessed predictors of glycemic control, QOL and diabetes self-management (DSM) of patients with DM in a tertiary hospital in Ghana. Methods We conducted a cross-sectional study involving face-to-face interviews of patients with DM attending clinic using structured questionnaires and validated study instruments as well as review of medical records. A multivariable logistic regression analysis was used to identify independent factors associated with good glycemic control, poor QOL and poor DSM practices. Results The study involved 360 patients with mean age of 62.5 ± 11.6 years and mean FBG of 9.0 ± 4.8 mmol/L, of which 40.8% had FBG < 7 mmol/L. Patients who were not on insulin(aOR 1.82; 95% CI 1.12–2.96, p = 0.017) were more likely to have good glycemic control. Urban residence (aOR 0.24; 95% CI 0.06–0.87, p = 0.030) was protective of having poor QOL. However, poor DSM(aOR 18.30; 95% CI 7.98–44.5, p < 0.001) and recent hospitalization(within the past 3 months) (aOR 4.58; 95% CI 1.58–13.26, p = 0.005) had higher odds of poor QOL. Patients who were divorced(aOR 6.92; 95% CI 1.24–43.20, p = 0.031) had higher odds of poor DSM, while having attended the clinic for more than 3 years(aOR 0.32; 95% CI 0.13–0.84, p = 0.018) was protective of poor DSM. Conclusion 4 out of 10 patients attending diabetes clinic are well controlled. Not being on insulin is independently associated with good glycemic control. Urban residence, DSM and recent hospitalization are associated with QOL while being divorced and duration in clinic predict DSM. Prevention of acute hospitalizations and promotion of good self-management among patients with diabetes can improve their quality of life.
AB - Background The burden of diabetes mellitus (DM) in Sub-Saharan Africa is high and continues to increase. Effective DM management focuses on key goals such as glycemic control, prevention of complications and improvement of quality of life (QOL). This study therefore assessed predictors of glycemic control, QOL and diabetes self-management (DSM) of patients with DM in a tertiary hospital in Ghana. Methods We conducted a cross-sectional study involving face-to-face interviews of patients with DM attending clinic using structured questionnaires and validated study instruments as well as review of medical records. A multivariable logistic regression analysis was used to identify independent factors associated with good glycemic control, poor QOL and poor DSM practices. Results The study involved 360 patients with mean age of 62.5 ± 11.6 years and mean FBG of 9.0 ± 4.8 mmol/L, of which 40.8% had FBG < 7 mmol/L. Patients who were not on insulin(aOR 1.82; 95% CI 1.12–2.96, p = 0.017) were more likely to have good glycemic control. Urban residence (aOR 0.24; 95% CI 0.06–0.87, p = 0.030) was protective of having poor QOL. However, poor DSM(aOR 18.30; 95% CI 7.98–44.5, p < 0.001) and recent hospitalization(within the past 3 months) (aOR 4.58; 95% CI 1.58–13.26, p = 0.005) had higher odds of poor QOL. Patients who were divorced(aOR 6.92; 95% CI 1.24–43.20, p = 0.031) had higher odds of poor DSM, while having attended the clinic for more than 3 years(aOR 0.32; 95% CI 0.13–0.84, p = 0.018) was protective of poor DSM. Conclusion 4 out of 10 patients attending diabetes clinic are well controlled. Not being on insulin is independently associated with good glycemic control. Urban residence, DSM and recent hospitalization are associated with QOL while being divorced and duration in clinic predict DSM. Prevention of acute hospitalizations and promotion of good self-management among patients with diabetes can improve their quality of life.
UR - https://www.scopus.com/pages/publications/105009845069
U2 - 10.1371/journal.pone.0317075
DO - 10.1371/journal.pone.0317075
M3 - Article
AN - SCOPUS:105009845069
SN - 1932-6203
VL - 20
JO - PLoS ONE
JF - PLoS ONE
IS - 7 July
M1 - e0317075
ER -
