Plasmodium falciparum parasites expressing pregnancy-specific variant surface antigens adhere strongly to the choriocarcinoma cell line BeWo

Rikke N. Haase; Rosette Megnekou; Maja Lundquist; Michael F. Ofori; Lars Hviid; Trine Staalsoe

doi:10.1128/IAI.74.5.3035-3038.2006

Plasmodium falciparum parasites expressing pregnancy-specific variant surface antigens adhere strongly to the choriocarcinoma cell line BeWo

Rikke N. Haase
, Rosette Megnekou
, Maja Lundquist
, Michael F. Ofori
, Lars Hviid
, Trine Staalsoe

Rigshospitalet
University of Ghana

Research output: Contribution to journal › Article › peer-review

49 Citations (Scopus)

Abstract

Placenta-sequestering Plasmodium falciparum parasites causing pregnancy-associated malaria express pregnancy-specific variant surface antigens (VSA_PAM). We report here that VSA_PAM-expressing patient isolates adhere strongly to the choriocarcinoma cell line BeWo and that the BeWo line can be used to efficiently select for VSA_PAM expression in vitro.

Original language	English
Pages (from-to)	3035-3038
Number of pages	4
Journal	Infection and Immunity
Volume	74
Issue number	5
DOIs	https://doi.org/10.1128/IAI.74.5.3035-3038.2006
Publication status	Published - May 2006
Externally published	Yes

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SDG 3 Good Health and Well-being

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10.1128/IAI.74.5.3035-3038.2006

Cite this

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title = "Plasmodium falciparum parasites expressing pregnancy-specific variant surface antigens adhere strongly to the choriocarcinoma cell line BeWo",

abstract = "Placenta-sequestering Plasmodium falciparum parasites causing pregnancy-associated malaria express pregnancy-specific variant surface antigens (VSAPAM). We report here that VSAPAM-expressing patient isolates adhere strongly to the choriocarcinoma cell line BeWo and that the BeWo line can be used to efficiently select for VSAPAM expression in vitro.",

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AU - Haase, Rikke N.

AU - Megnekou, Rosette

AU - Lundquist, Maja

AU - Ofori, Michael F.

AU - Hviid, Lars

AU - Staalsoe, Trine

PY - 2006/5

Y1 - 2006/5

N2 - Placenta-sequestering Plasmodium falciparum parasites causing pregnancy-associated malaria express pregnancy-specific variant surface antigens (VSAPAM). We report here that VSAPAM-expressing patient isolates adhere strongly to the choriocarcinoma cell line BeWo and that the BeWo line can be used to efficiently select for VSAPAM expression in vitro.

AB - Placenta-sequestering Plasmodium falciparum parasites causing pregnancy-associated malaria express pregnancy-specific variant surface antigens (VSAPAM). We report here that VSAPAM-expressing patient isolates adhere strongly to the choriocarcinoma cell line BeWo and that the BeWo line can be used to efficiently select for VSAPAM expression in vitro.

UR - https://www.scopus.com/pages/publications/33646358466

U2 - 10.1128/IAI.74.5.3035-3038.2006

DO - 10.1128/IAI.74.5.3035-3038.2006

M3 - Article

C2 - 16622246

AN - SCOPUS:33646358466

SN - 0019-9567

VL - 74

SP - 3035

EP - 3038

JO - Infection and Immunity

JF - Infection and Immunity

IS - 5

ER -

Plasmodium falciparum parasites expressing pregnancy-specific variant surface antigens adhere strongly to the choriocarcinoma cell line BeWo

Abstract

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