Novel nanocrystal clay materials with potential bone cells growth enhancement or inhibition characteristics in vitro

Elvis K. Tiburu, Benjamin W. Kankpeyeng, Samuel N. Nkumbaan, Ali A. Salifu, Jianqin Zhuang

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)

Abstract

The application of clay nanocrystals in healing has gained popularity in recent years. T objective of this work was to investigate whether healing clays obtained from different geographi locations could influence differential cell growth. X-ray diffraction analyses of both nanocrys materials revealed orthorhombic chamosite structure with lattice parameters: a =15 Å, b= 8 Å a c=7 Å whereas energy dispersive x-ray results showed the presence of Al, Si, Fe and O in b materials. However the porosity measurements of the two materials revealed different p structures. Both materials were tested on human fetal osteoblast cells and the results show differential cell growth in vitro. The results underscore the significance of pore structures in c response as against the chemical composition or the structure of the material. Future mechanis evaluation would be conducted to better understand the pathways leading to the increased/decrea osteoblast adhesion and proliferation by these materials and possible modification of the cl materials for biomedical applications.

Original languageEnglish
Pages (from-to)45-60
Number of pages16
JournalJournal of Biomimetics, Biomaterials and Biomedical Engineering
Volume30
DOIs
Publication statusPublished - 2017

Keywords

  • Archaeology
  • EDX
  • Ethnographic clay
  • FTIR
  • Osteoblasts
  • XRD

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