TY - JOUR
T1 - Multilingual validation of the questionnaire for verifying stroke-free status in West Africa
AU - Sarfo, Fred
AU - Gebregziabher, Mulugeta
AU - Ovbiagele, Bruce
AU - Akinyemi, Rufus
AU - Owolabi, Lukman
AU - Obiako, Reginald
AU - Akpa, Onoja
AU - Armstrong, Kevin
AU - Akpalu, Albert
AU - Adamu, Sheila
AU - Obese, Vida
AU - Boa-Antwi, Nana
AU - Appiah, Lambert
AU - Arulogun, Oyedunni
AU - Mensah, Yaw
AU - Adeoye, Abiodun
AU - Tosin, Aridegbe
AU - Adeleye, Osimhiarherhuo
AU - Tabi-Ajayi, Eric
AU - Phillip, Ibinaiye
AU - Sani, Abubakar
AU - Isah, Suleiman
AU - Tabari, Nasir
AU - Mande, Aliyu
AU - Agunloye, Atinuke
AU - Ogbole, Godwin
AU - Akinyemi, Joshua
AU - Laryea, Ruth
AU - Melikam, Sylvia
AU - Uvere, Ezinne
AU - Adekunle, Gregory
AU - Kehinde, Salaam
AU - Azuh, Paschal
AU - Dambatta, Abdul
AU - Ishaq, Naser
AU - Saulson, Raelle
AU - Arnett, Donna
AU - Tiwari, Hemnant
AU - Jenkins, Carolyn
AU - Lackland, Dan
AU - Owolabi, Mayowa
N1 - Publisher Copyright:
© 2015 American Heart Association, Inc.
PY - 2016/1/1
Y1 - 2016/1/1
N2 - Background and Purpose - The Questionnaire for Verifying Stroke-Free Status (QVSFS), a method for verifying stroke-free status in participants of clinical, epidemiological, and genetic studies, has not been validated in low-income settings where populations have limited knowledge of stroke symptoms. We aimed to validate QVSFS in 3 languages, Yoruba, Hausa and Akan, for ascertainment of stroke-free status of control subjects enrolled in an on-going stroke epidemiological study in West Africa. Methods - Data were collected using a cross-sectional study design where 384 participants were consecutively recruited from neurology and general medicine clinics of 5 tertiary referral hospitals in Nigeria and Ghana. Ascertainment of stroke status was by neurologists using structured neurological examination, review of case records, and neuroimaging (gold standard). Relative performance of QVSFS without and with pictures of stroke symptoms (pictograms) was assessed using sensitivity, specificity, positive predictive value, and negative predictive value. Results - The overall median age of the study participants was 54 years and 48.4% were males. Of 165 stroke cases identified by gold standard, 98% were determined to have had stroke, whereas of 219 without stroke 87% were determined to be stroke-free by QVSFS. Negative predictive value of the QVSFS across the 3 languages was 0.97 (range, 0.93-1.00), sensitivity, specificity, and positive predictive value were 0.98, 0.82, and 0.80, respectively. Agreement between the questionnaire with and without the pictogram was excellent/strong with Cohen k=0.92. Conclusions - QVSFS is a valid tool for verifying stroke-free status across culturally diverse populations in West Africa.
AB - Background and Purpose - The Questionnaire for Verifying Stroke-Free Status (QVSFS), a method for verifying stroke-free status in participants of clinical, epidemiological, and genetic studies, has not been validated in low-income settings where populations have limited knowledge of stroke symptoms. We aimed to validate QVSFS in 3 languages, Yoruba, Hausa and Akan, for ascertainment of stroke-free status of control subjects enrolled in an on-going stroke epidemiological study in West Africa. Methods - Data were collected using a cross-sectional study design where 384 participants were consecutively recruited from neurology and general medicine clinics of 5 tertiary referral hospitals in Nigeria and Ghana. Ascertainment of stroke status was by neurologists using structured neurological examination, review of case records, and neuroimaging (gold standard). Relative performance of QVSFS without and with pictures of stroke symptoms (pictograms) was assessed using sensitivity, specificity, positive predictive value, and negative predictive value. Results - The overall median age of the study participants was 54 years and 48.4% were males. Of 165 stroke cases identified by gold standard, 98% were determined to have had stroke, whereas of 219 without stroke 87% were determined to be stroke-free by QVSFS. Negative predictive value of the QVSFS across the 3 languages was 0.97 (range, 0.93-1.00), sensitivity, specificity, and positive predictive value were 0.98, 0.82, and 0.80, respectively. Agreement between the questionnaire with and without the pictogram was excellent/strong with Cohen k=0.92. Conclusions - QVSFS is a valid tool for verifying stroke-free status across culturally diverse populations in West Africa.
KW - Ghana
KW - cross-sectional studies
KW - neurology
KW - sensitivity and specificity
KW - stroke
UR - http://www.scopus.com/inward/record.url?scp=84952629341&partnerID=8YFLogxK
U2 - 10.1161/STROKEAHA.115.010374
DO - 10.1161/STROKEAHA.115.010374
M3 - Article
C2 - 26578660
AN - SCOPUS:84952629341
SN - 0039-2499
VL - 47
SP - 167
EP - 172
JO - Stroke
JF - Stroke
IS - 1
ER -