TY - JOUR
T1 - Monitoring parasite diversity for malaria elimination in sub-Saharan Africa
AU - Ghansah, Anita
AU - Amenga-Etego, Lucas
AU - Amambua-Ngwa, Alfred
AU - Andagalu, Ben
AU - Apinjoh, Tobias
AU - Bouyou-Akotet, Marielle
AU - Cornelius, Victoria
AU - Golassa, Lemu
AU - Andrianaranjaka, Voahangy Hanitriniaina
AU - Ishengoma, Deus
AU - Johnson, Kimberly
AU - Kamau, Edwin
AU - Maïga-Ascofaré, Oumou
AU - Mumba, Dieudonne
AU - Tindana, Paulina
AU - Tshefu-Kitoto, Antoinette
AU - Randrianarivelojosia, Milijaona
AU - William, Yavo
AU - Kwiatkowski, Dominic P.
AU - Djimde, Abdoulaye A.
PY - 2014/9/12
Y1 - 2014/9/12
N2 - The African continent continues to bear the greatest burden of malaria and the greatest diversity of parasites, mosquito vectors, and human victims. The evolutionary plasticity of malaria parasites and their vectors is a major obstacle to eliminating the disease. Of current concern is the recently reported emergence of resistance to the front-line drug, artemisinin, in South-East Asia in Plasmodium falciparum, which calls for preemptive surveillance of the African parasite population for genetic markers of emerging drug resistance. Here we describe the Plasmodium Diversity Network Africa (PDNA), which has been established across 11 countries in sub-Saharan Africa to ensure that African scientists are enabled to work together and to play a key role in the global effort for tracking and responding to this public health threat.
AB - The African continent continues to bear the greatest burden of malaria and the greatest diversity of parasites, mosquito vectors, and human victims. The evolutionary plasticity of malaria parasites and their vectors is a major obstacle to eliminating the disease. Of current concern is the recently reported emergence of resistance to the front-line drug, artemisinin, in South-East Asia in Plasmodium falciparum, which calls for preemptive surveillance of the African parasite population for genetic markers of emerging drug resistance. Here we describe the Plasmodium Diversity Network Africa (PDNA), which has been established across 11 countries in sub-Saharan Africa to ensure that African scientists are enabled to work together and to play a key role in the global effort for tracking and responding to this public health threat.
UR - http://www.scopus.com/inward/record.url?scp=84907192656&partnerID=8YFLogxK
U2 - 10.1126/science.1259423
DO - 10.1126/science.1259423
M3 - Review article
C2 - 25214619
AN - SCOPUS:84907192656
SN - 0036-8075
VL - 345
SP - 1297
EP - 1298
JO - Science
JF - Science
IS - 6202
ER -