Methicillin resistant staphylococcus aureus and extended spectrum betalactamase producing enterobacteriaceae: A Therapeutic Challenge in the 21st Century

Eric S. Donkor, Francis S. Codjoe, Francis S. Codjoe

Research output: Contribution to journalReview articlepeer-review

10 Citations (Scopus)

Abstract

Antimicrobial resistance is one of the greatest global threats to human health in recent times and it limits the achievement of several of the Sustainable Development Goals. Methicillin-Resistant Staphylococcus aureus (MRSA) and Extended-Spectrum Beta-Lactamase (ESBL) producing Enterobacteriaceae are among the most important multidrug resistant bacterial pathogens. MRSA and ESBL-producing Enterobacteriaceae have evolved significantly over the last few decades with important clinical and epidemiological implications. Given the slow progress of development of new antibiotics in recent times, it is likely that these multidrug resistant pathogens will have a greater impact on public health in the 21st Century, unless other effective control measures are instituted. Effective infection control strategies coupled with antibiotic stewardship programs are required to limit the spread and burden of MRSA and ESBL-producing Enterobacteriacae.

Original languageEnglish
Pages (from-to)94-100
Number of pages7
JournalOpen Microbiology Journal
Volume13
Issue number1
DOIs
Publication statusPublished - 2019

Keywords

  • AMR
  • ESBL
  • Escherichia coli
  • Klebsiella pneumoniae
  • Methicillin
  • Staphylococcus aureus

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