Metabolic Syndrome and Kidney Diseases

Vincent Boima; Alexander B. Agyekum; Augustus K. Eduafo

doi:10.1007/978-3-031-40116-9_57

Metabolic Syndrome and Kidney Diseases

Vincent Boima, Alexander B. Agyekum, Augustus K. Eduafo

Department of Medicine And Therapeutics

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Abstract

The metabolic syndrome (MetS) affects 20–25% of people worldwide and increases the risk of cardiovascular disease (CVD). MetS is associated with kidney abnormalities, including activation of the renin-angiotensin-aldosterone system (RAAS), glomerular hyperfiltration, podocyte injury, albuminuria, and fibrosis. This chapter describes the epidemiology and pathogenesis of chronic kidney disease (CKD) in MetS, including the roles of obesity, insulin resistance, diabetes, adipokines, oxidative stress, inflammation, and endothelial dysfunction, and the current and future strategies for prevention and treatment of CKD.

Original language	English
Title of host publication	Metabolic Syndrome
Subtitle of host publication	A Comprehensive Textbook, Second Edition
Publisher	Springer International Publishing
Pages	675-691
Number of pages	17
ISBN (Electronic)	9783031401169
ISBN (Print)	9783031401152
DOIs	https://doi.org/10.1007/978-3-031-40116-9_57
Publication status	Published - 1 Jan 2023

Keywords

Albuminuria
Diabetes
Hypertension
Inflammation
Kidney disease
Obesity

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1007/978-3-031-40116-9_57

Cite this

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abstract = "The metabolic syndrome (MetS) affects 20–25\% of people worldwide and increases the risk of cardiovascular disease (CVD). MetS is associated with kidney abnormalities, including activation of the renin-angiotensin-aldosterone system (RAAS), glomerular hyperfiltration, podocyte injury, albuminuria, and fibrosis. This chapter describes the epidemiology and pathogenesis of chronic kidney disease (CKD) in MetS, including the roles of obesity, insulin resistance, diabetes, adipokines, oxidative stress, inflammation, and endothelial dysfunction, and the current and future strategies for prevention and treatment of CKD.",

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AU - Agyekum, Alexander B.

AU - Eduafo, Augustus K.

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Y1 - 2023/1/1

N2 - The metabolic syndrome (MetS) affects 20–25% of people worldwide and increases the risk of cardiovascular disease (CVD). MetS is associated with kidney abnormalities, including activation of the renin-angiotensin-aldosterone system (RAAS), glomerular hyperfiltration, podocyte injury, albuminuria, and fibrosis. This chapter describes the epidemiology and pathogenesis of chronic kidney disease (CKD) in MetS, including the roles of obesity, insulin resistance, diabetes, adipokines, oxidative stress, inflammation, and endothelial dysfunction, and the current and future strategies for prevention and treatment of CKD.

AB - The metabolic syndrome (MetS) affects 20–25% of people worldwide and increases the risk of cardiovascular disease (CVD). MetS is associated with kidney abnormalities, including activation of the renin-angiotensin-aldosterone system (RAAS), glomerular hyperfiltration, podocyte injury, albuminuria, and fibrosis. This chapter describes the epidemiology and pathogenesis of chronic kidney disease (CKD) in MetS, including the roles of obesity, insulin resistance, diabetes, adipokines, oxidative stress, inflammation, and endothelial dysfunction, and the current and future strategies for prevention and treatment of CKD.

KW - Albuminuria

KW - Diabetes

KW - Hypertension

KW - Inflammation

KW - Kidney disease

KW - Obesity

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EP - 691

BT - Metabolic Syndrome

PB - Springer International Publishing

ER -

Metabolic Syndrome and Kidney Diseases

Abstract

Keywords

UN SDGs

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