Malaria artemisinin resistance: an extracellular vesicles export hypothesis

Kwesi Z. Tandoh, Collins M. Morang'a, Michael Wilson, Neils B. Quashie, Nancy O. Duah-Quashie

Research output: Contribution to journalShort surveypeer-review

5 Citations (Scopus)

Abstract

Plasmodium falciparum causes malaria, and its resistance to artemisinin (ART) – a drug used for managing malaria – threatens to interfere with the effective control of malaria. ART resistance (ARTr) is driven by increased tolerance to oxidative stress and reduced haemoglobin trafficking to the food vacuole. We discuss how extracellular vesicles (EVs) may play a role in developing ARTr.

Original languageEnglish
Pages (from-to)614-617
Number of pages4
JournalTrends in Parasitology
Volume38
Issue number8
DOIs
Publication statusPublished - Aug 2022
Externally publishedYes

Keywords

  • artemisinin resistance
  • extracellular vesicles
  • hypothetical model

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