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Leveraging data science to understand and address multimorbidity in sub-Saharan Africa: The MADIVA protocol

  • Kerry Glover
  • , Tabitha Osler
  • , Kayode Adetunji
  • , Tanya Akumu
  • , Gershim Asiki
  • , Diana Awuor
  • , Palwendé Boua
  • , Victoria Bronstein
  • , Joan Byamugisha
  • , Jacques D. Du Toit
  • , Barry Dwolatzky
  • , Jaya George
  • , Paul A. Harris
  • , Kobus Herbst
  • , Karen Hofman
  • , Celeste Holden
  • , Samuel Iddi
  • , Damazo T. Kadengye
  • , Kathleen Kahn
  • , Michelle Kamp
  • Nhlamulo Khoza, Faith Kimongo, Isaac Kisiangani, Dekuwin E. Kogda, Michael Klipin, Stephen P. Levitt, Dylan Maghini, Karabo Maila, Eric Maimela, Daniel Maina Nderitu, Ndivhuwo Makondo, Molulaqhooa Linda Maoyi, Reineilwe Given Mashaba, Nkosinathi Gabriel Masilela, Theophilous Mathema, Phelelani Thokozani Mpangase, Daphine T. Nyachowe, Daniel Ohene-Kwofie, Helen Robertson, Skyler Speakman, Evelyn Thsehla, Siphiwe A. Thwala, Roy Zent, Francesc Xavier Gómez-Olivé, Chodziwadziwa W. Kabudula, Patrick Opiyo Owili, Catherine Kyobutungi, Michèle Ramsay, Stephen Tollman, Scott Hazelhurst
  • University of the Witwatersrand, Johannesburg
  • IBM
  • African Population and Health Research Center
  • Karolinska Institutet
  • Health Sciences Research Institute (IRSS)
  • University of the Witwatersrand
  • Swiss Tropical and Public Health Institute Swiss TPH
  • University of Basel
  • National Health Laboratory Service
  • Vanderbilt University
  • South African Medical Research Council
  • Africa Health Research Institute
  • King’s College London
  • Academic Medical Centre
  • Stanford University
  • University of Limpopo
  • University of the Witwatersrand
  • INDEPTH Network

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)

Abstract

Introduction Multimorbidity (MM), defined as two or more chronic diseases in an individual, is linked to adverse outcomes. MM is increasing in sub-Saharan Africa due to rapidly advancing epidemiological and social transitions. The Multimorbidity in Africa: Digital Innovation, Visualisation and Application Research Hub (MADIVA) aims to address MM by developing data science solutions informed by stakeholder engagement. Methods and analysis MADIVA uses complex, individual-level datasets from research centres in rural Bushbuckridge, South Africa and urban Nairobi, Kenya. These datasets will be harmonised, linked and curated, and then used to develop MM risk prediction models, novel data science methods and interactive dashboards for research and clinical use. Pilot projects and mentorship programmes will support data science capacity development. Ethics and dissemination Ethics approval has been granted. Dissemination will occur through scientific meetings and publications. MADIVA is committed to making data FAIR: findable, accessible, interoperable and reusable.

Original languageEnglish
Article numbere101294
JournalJournal of Innovation in Health Informatics
Volume32
Issue number1
DOIs
Publication statusPublished - 10 Jul 2025

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