TY - JOUR
T1 - Impact of exercise intensity on oxidative stress and selected metabolic markers in young adults in Ghana
AU - Diaba-Nuhoho, Patrick
AU - Ofori, Emmanuel Kwaku
AU - Asare-Anane, Henry
AU - Oppong, Sylvester Yaw
AU - Boamah, Isaac
AU - Blackhurst, Dee
N1 - Publisher Copyright:
© 2018 The Author(s).
PY - 2018/9/3
Y1 - 2018/9/3
N2 - Objective: This study aimed to evaluate the effect of different levels of exercise on markers of oxidative stress and selected metabolic parameters in Ghanaian young adults. Results: Significant increases in a marker of oxidative stress malondialdehyde and antioxidants such as superoxide dismutase and uric acid were observed in the exercisers compared with the inactive group (p < 0.05). Total cholesterol and high density lipoprotein levels were significantly different (p < 0.05) between the two groups. Positive associations between exercise intensity, antioxidant concentration and malondialdehyde were observed within the exercise group for vigorous exercise with regards to uric acid, superoxide dismutase and malondialdehyde (r = 0.512, p = 0.004; r = 0.810, p = 0.001; r = 0.715, p = 0.001) respectively and moderate exercise vs malondialdehyde (r = 0.841, p = 0.001) compared to the inactive group. Exercise participants performed more vigorous exercise (p < 0.001), moderate exercise (p < 0.001) and more walking (p < 0.001) compared with the inactive group while the inactive group exhibited more sitting (p < 0.001). The study provides a first report on the risk associated with increase in oxidative stress and the importance of walking as a health promotion intervention among young Ghanaian adults.
AB - Objective: This study aimed to evaluate the effect of different levels of exercise on markers of oxidative stress and selected metabolic parameters in Ghanaian young adults. Results: Significant increases in a marker of oxidative stress malondialdehyde and antioxidants such as superoxide dismutase and uric acid were observed in the exercisers compared with the inactive group (p < 0.05). Total cholesterol and high density lipoprotein levels were significantly different (p < 0.05) between the two groups. Positive associations between exercise intensity, antioxidant concentration and malondialdehyde were observed within the exercise group for vigorous exercise with regards to uric acid, superoxide dismutase and malondialdehyde (r = 0.512, p = 0.004; r = 0.810, p = 0.001; r = 0.715, p = 0.001) respectively and moderate exercise vs malondialdehyde (r = 0.841, p = 0.001) compared to the inactive group. Exercise participants performed more vigorous exercise (p < 0.001), moderate exercise (p < 0.001) and more walking (p < 0.001) compared with the inactive group while the inactive group exhibited more sitting (p < 0.001). The study provides a first report on the risk associated with increase in oxidative stress and the importance of walking as a health promotion intervention among young Ghanaian adults.
KW - Antioxidants
KW - Different intensity exercise
KW - Reactive oxygen species
UR - http://www.scopus.com/inward/record.url?scp=85052745532&partnerID=8YFLogxK
U2 - 10.1186/s13104-018-3758-y
DO - 10.1186/s13104-018-3758-y
M3 - Article
C2 - 30176917
AN - SCOPUS:85052745532
SN - 1756-0500
VL - 11
JO - BMC Research Notes
JF - BMC Research Notes
IS - 1
M1 - 634
ER -