Identification of Amino Acid Substitutions Within the VP7 Genes of G2 Rotavirus Strains in Ghana

Susan A. Damanka; Chantal A. Agbemabiese; Belinda L. Lartey; Francis E. Dennis; Frederick K. Asamoah; Theophilus K. Adiku; Christabel C. Enweronu-Laryea; Kwamena W. Sagoe; Michael F. Ofori; George E. Armah

doi:10.1097/INF.0000000000002037

Identification of Amino Acid Substitutions Within the VP7 Genes of G2 Rotavirus Strains in Ghana

Susan A. Damanka
, Chantal A. Agbemabiese
, Belinda L. Lartey
, Francis E. Dennis
, Frederick K. Asamoah
, Theophilus K. Adiku
, Christabel C. Enweronu-Laryea
, Kwamena W. Sagoe
, Michael F. Ofori
, George E. Armah

Noguchi Memorial Institute for Medical Research

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

Abstract

We used the dideoxynucleotide chain termination method to determine the strains of nine non-typeable rotavirus enzyme immunoassay-positive samples, which were identified as G2. We detected nucleotide changes in the primer-binding region and amino acid substitutions within the VP7 protein of the G2 rotavirus strains. Genotyping primers need to be updated regularly.

Original language	English
Pages (from-to)	1172-1174
Number of pages	3
Journal	Pediatric Infectious Disease Journal
Volume	37
Issue number	11
DOIs	https://doi.org/10.1097/INF.0000000000002037
Publication status	Published - 1 Nov 2018
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

G2 genotype
Ghana
Group A rotaviruses
Phylogenetic analysis

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10.1097/INF.0000000000002037

Cite this

Damanka, S. A., Agbemabiese, C. A., Lartey, B. L., Dennis, F. E., Asamoah, F. K., Adiku, T. K., Enweronu-Laryea, C. C., Sagoe, K. W., Ofori, M. F., & Armah, G. E. (2018). Identification of Amino Acid Substitutions Within the VP7 Genes of G2 Rotavirus Strains in Ghana. Pediatric Infectious Disease Journal, 37(11), 1172-1174. https://doi.org/10.1097/INF.0000000000002037

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abstract = "We used the dideoxynucleotide chain termination method to determine the strains of nine non-typeable rotavirus enzyme immunoassay-positive samples, which were identified as G2. We detected nucleotide changes in the primer-binding region and amino acid substitutions within the VP7 protein of the G2 rotavirus strains. Genotyping primers need to be updated regularly.",

keywords = "G2 genotype, Ghana, Group A rotaviruses, Phylogenetic analysis",

author = "Damanka, \{Susan A.\} and Agbemabiese, \{Chantal A.\} and Lartey, \{Belinda L.\} and Dennis, \{Francis E.\} and Asamoah, \{Frederick K.\} and Adiku, \{Theophilus K.\} and Enweronu-Laryea, \{Christabel C.\} and Sagoe, \{Kwamena W.\} and Ofori, \{Michael F.\} and Armah, \{George E.\}",

year = "2018",

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doi = "10.1097/INF.0000000000002037",

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AU - Damanka, Susan A.

AU - Agbemabiese, Chantal A.

AU - Lartey, Belinda L.

AU - Dennis, Francis E.

AU - Asamoah, Frederick K.

AU - Adiku, Theophilus K.

AU - Enweronu-Laryea, Christabel C.

AU - Sagoe, Kwamena W.

AU - Ofori, Michael F.

AU - Armah, George E.

PY - 2018/11/1

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AB - We used the dideoxynucleotide chain termination method to determine the strains of nine non-typeable rotavirus enzyme immunoassay-positive samples, which were identified as G2. We detected nucleotide changes in the primer-binding region and amino acid substitutions within the VP7 protein of the G2 rotavirus strains. Genotyping primers need to be updated regularly.

KW - G2 genotype

KW - Ghana

KW - Group A rotaviruses

KW - Phylogenetic analysis

UR - https://www.scopus.com/pages/publications/85054898459

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DO - 10.1097/INF.0000000000002037

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JO - Pediatric Infectious Disease Journal

JF - Pediatric Infectious Disease Journal

IS - 11

ER -

Identification of Amino Acid Substitutions Within the VP7 Genes of G2 Rotavirus Strains in Ghana

Abstract

UN SDGs

Keywords

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