Identification of Amino Acid Substitutions Within the VP7 Genes of G2 Rotavirus Strains in Ghana

Susan A. Damanka; Chantal A. Agbemabiese; Belinda L. Lartey; Francis E. Dennis; Frederick K. Asamoah; Theophilus K. Adiku; Christabel C. Enweronu-Laryea; Kwamena W. Sagoe; Michael F. Ofori; George E. Armah

doi:10.1097/INF.0000000000002037

Identification of Amino Acid Substitutions Within the VP7 Genes of G2 Rotavirus Strains in Ghana

Susan A. Damanka, Chantal A. Agbemabiese, Belinda L. Lartey, Francis E. Dennis, Frederick K. Asamoah, Theophilus K. Adiku, Christabel C. Enweronu-Laryea, Kwamena W. Sagoe, Michael F. Ofori, George E. Armah

Noguchi Memorial Institute for Medical Research

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

Abstract

We used the dideoxynucleotide chain termination method to determine the strains of nine non-typeable rotavirus enzyme immunoassay-positive samples, which were identified as G2. We detected nucleotide changes in the primer-binding region and amino acid substitutions within the VP7 protein of the G2 rotavirus strains. Genotyping primers need to be updated regularly.

Original language	English
Pages (from-to)	1172-1174
Number of pages	3
Journal	Pediatric Infectious Disease Journal
Volume	37
Issue number	11
DOIs	https://doi.org/10.1097/INF.0000000000002037
Publication status	Published - 1 Nov 2018
Externally published	Yes

Keywords

G2 genotype
Ghana
Group A rotaviruses
Phylogenetic analysis

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1097/INF.0000000000002037

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Damanka, S. A., Agbemabiese, C. A., Lartey, B. L., Dennis, F. E., Asamoah, F. K., Adiku, T. K., Enweronu-Laryea, C. C., Sagoe, K. W., Ofori, M. F., & Armah, G. E. (2018). Identification of Amino Acid Substitutions Within the VP7 Genes of G2 Rotavirus Strains in Ghana. Pediatric Infectious Disease Journal, 37(11), 1172-1174. https://doi.org/10.1097/INF.0000000000002037

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title = "Identification of Amino Acid Substitutions Within the VP7 Genes of G2 Rotavirus Strains in Ghana",

abstract = "We used the dideoxynucleotide chain termination method to determine the strains of nine non-typeable rotavirus enzyme immunoassay-positive samples, which were identified as G2. We detected nucleotide changes in the primer-binding region and amino acid substitutions within the VP7 protein of the G2 rotavirus strains. Genotyping primers need to be updated regularly.",

keywords = "G2 genotype, Ghana, Group A rotaviruses, Phylogenetic analysis",

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year = "2018",

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doi = "10.1097/INF.0000000000002037",

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AU - Damanka, Susan A.

AU - Agbemabiese, Chantal A.

AU - Lartey, Belinda L.

AU - Dennis, Francis E.

AU - Asamoah, Frederick K.

AU - Adiku, Theophilus K.

AU - Enweronu-Laryea, Christabel C.

AU - Sagoe, Kwamena W.

AU - Ofori, Michael F.

AU - Armah, George E.

PY - 2018/11/1

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AB - We used the dideoxynucleotide chain termination method to determine the strains of nine non-typeable rotavirus enzyme immunoassay-positive samples, which were identified as G2. We detected nucleotide changes in the primer-binding region and amino acid substitutions within the VP7 protein of the G2 rotavirus strains. Genotyping primers need to be updated regularly.

KW - G2 genotype

KW - Ghana

KW - Group A rotaviruses

KW - Phylogenetic analysis

UR - https://www.scopus.com/pages/publications/85054898459

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IS - 11

ER -

Identification of Amino Acid Substitutions Within the VP7 Genes of G2 Rotavirus Strains in Ghana

Abstract

Keywords

UN SDGs

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