Identification of Amino Acid Substitutions Within the VP7 Genes of G2 Rotavirus Strains in Ghana

Susan A. Damanka, Chantal A. Agbemabiese, Belinda L. Lartey, Francis E. Dennis, Frederick K. Asamoah, Theophilus K. Adiku, Christabel C. Enweronu-Laryea, Kwamena W. Sagoe, Michael F. Ofori, George E. Armah

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)

Abstract

We used the dideoxynucleotide chain termination method to determine the strains of nine non-typeable rotavirus enzyme immunoassay-positive samples, which were identified as G2. We detected nucleotide changes in the primer-binding region and amino acid substitutions within the VP7 protein of the G2 rotavirus strains. Genotyping primers need to be updated regularly.

Original languageEnglish
Pages (from-to)1172-1174
Number of pages3
JournalPediatric Infectious Disease Journal
Volume37
Issue number11
DOIs
Publication statusPublished - 1 Nov 2018
Externally publishedYes

Keywords

  • G2 genotype
  • Ghana
  • Group A rotaviruses
  • Phylogenetic analysis

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