TY - JOUR
T1 - HIV and malaria prevalence among pregnant women with and without pre-eclampsia at the Atua Government Hospital in Ghana’s eastern region
AU - Orish, Verner N.
AU - Ansong-Boateng, Jude
AU - Puplampu, Prince N.
AU - Ibine, Bolade
AU - Azanu, Wisdom
AU - Amoh, Michael Y.
AU - Lokpo, Sylvester Y.
AU - Afeke, Innocent
AU - Alalbila, Thelma Mpoku
AU - Agordoh, Percival D.
AU - Marinkovic, Aleksandra
AU - Sanyaolu, Adekunle
N1 - Publisher Copyright:
© 2022 International Federation of Gynecology and Obstetrics.
PY - 2022/12
Y1 - 2022/12
N2 - Objective: To evaluate the association of malaria and HIV with pre-eclampsia by evaluating their prevalence among pregnant women. Methods: Using a case–control study design, we randomly sampled the antenatal records of 125 pregnant women with clinician-diagnosed pre-eclampsia (cases) and 125 others without pre-eclampsia (controls) who visited Atua Government Hospital in the eastern region of Ghana between June 2014 and January 2017. All selected records had available routine HIV and malaria test results and were analyzed statistically. Results: In all 250 records, 122 (48.8%) were HIV positive and 35 (14.0%) had malaria. Of the 122 HIV-positive pregnant women, 29 (23.8%) were cases and 93 (76.2%) were controls; of the 35 women with malaria, one was in the case group (1/35, 2.9%) and the other 34 (97.1%) were in the control. Group. Pregnant women with pre-eclampsia had lower odds of HIV infection (odds ratio [OR] 0.10, 95% confidence interval [CI] 0.06–0.19: adjusted AOR 0.07, 95% CI 0.04–0.13, P < 0.001). Similarly, pregnant women with pre-eclampsia had lower odds of having malaria infection (OR 0.02, 95% CI 0.00–0.17, P = 0.025; adjusted OR 0.00, 95% CI 0.00–0.01, P < 0.001). Conclusions: Women with pre-eclampsia had lower odds of HIV and malaria infection in pregnancy.
AB - Objective: To evaluate the association of malaria and HIV with pre-eclampsia by evaluating their prevalence among pregnant women. Methods: Using a case–control study design, we randomly sampled the antenatal records of 125 pregnant women with clinician-diagnosed pre-eclampsia (cases) and 125 others without pre-eclampsia (controls) who visited Atua Government Hospital in the eastern region of Ghana between June 2014 and January 2017. All selected records had available routine HIV and malaria test results and were analyzed statistically. Results: In all 250 records, 122 (48.8%) were HIV positive and 35 (14.0%) had malaria. Of the 122 HIV-positive pregnant women, 29 (23.8%) were cases and 93 (76.2%) were controls; of the 35 women with malaria, one was in the case group (1/35, 2.9%) and the other 34 (97.1%) were in the control. Group. Pregnant women with pre-eclampsia had lower odds of HIV infection (odds ratio [OR] 0.10, 95% confidence interval [CI] 0.06–0.19: adjusted AOR 0.07, 95% CI 0.04–0.13, P < 0.001). Similarly, pregnant women with pre-eclampsia had lower odds of having malaria infection (OR 0.02, 95% CI 0.00–0.17, P = 0.025; adjusted OR 0.00, 95% CI 0.00–0.01, P < 0.001). Conclusions: Women with pre-eclampsia had lower odds of HIV and malaria infection in pregnancy.
KW - Ghana
KW - HIV
KW - Malaria
KW - pre-eclampsia
KW - pregnant woman
UR - http://www.scopus.com/inward/record.url?scp=85130324888&partnerID=8YFLogxK
U2 - 10.1002/ijgo.14255
DO - 10.1002/ijgo.14255
M3 - Article
C2 - 35514313
AN - SCOPUS:85130324888
SN - 0020-7292
VL - 159
SP - 912
EP - 917
JO - International Journal of Gynecology and Obstetrics
JF - International Journal of Gynecology and Obstetrics
IS - 3
ER -