TY - JOUR
T1 - Fetal middle cerebral artery Doppler indices and clinical application at Korle Bu Teaching Hospital, Accra, Ghana
AU - Seffah, Joseph D.
AU - Swarray-Deen, Alim
N1 - Publisher Copyright:
© 2016 International Federation of Gynecology and Obstetrics
PY - 2016/8/1
Y1 - 2016/8/1
N2 - Objective To determine normal ranges for various Doppler flow velocity indices of the fetal middle cerebral artery (MCA) and their trends in normal pregnancies at Korle Bu Teaching Hospital, Accra, Ghana. Methods A prospective cross-sectional study was conducted at Korle Bu Teaching Hospital in 2015. Included women had a singleton pregnancy of 20–40 weeks’ duration, dated using an early ultrasonography scan, and normal fetal growth. Interviews were conducted to collect data on sociodemographic characteristics, followed by Doppler ultrasonography of the MCA. The resistive index, pulsatility index, systolic-to-diastolic ratio, and peak systolic velocity of the MCA were determined for all participants. Results Overall, 458 pregnant women were recruited. The peak systolic velocity increased with advancing gestational age and a positive correlation of r = 0.725 (P < 0.001) was demonstrated between the peak systolic velocity and the gestational age. The resistive index, pulsatility index, and systolic-to-diastolic ratio of the MCA decreased with advancing gestational age in a parabolic pattern. Conclusion The reference curve for the peak systolic velocity increases with gestational age, whereas the other indices decrease in a parabolic pattern.
AB - Objective To determine normal ranges for various Doppler flow velocity indices of the fetal middle cerebral artery (MCA) and their trends in normal pregnancies at Korle Bu Teaching Hospital, Accra, Ghana. Methods A prospective cross-sectional study was conducted at Korle Bu Teaching Hospital in 2015. Included women had a singleton pregnancy of 20–40 weeks’ duration, dated using an early ultrasonography scan, and normal fetal growth. Interviews were conducted to collect data on sociodemographic characteristics, followed by Doppler ultrasonography of the MCA. The resistive index, pulsatility index, systolic-to-diastolic ratio, and peak systolic velocity of the MCA were determined for all participants. Results Overall, 458 pregnant women were recruited. The peak systolic velocity increased with advancing gestational age and a positive correlation of r = 0.725 (P < 0.001) was demonstrated between the peak systolic velocity and the gestational age. The resistive index, pulsatility index, and systolic-to-diastolic ratio of the MCA decreased with advancing gestational age in a parabolic pattern. Conclusion The reference curve for the peak systolic velocity increases with gestational age, whereas the other indices decrease in a parabolic pattern.
KW - Accra
KW - Doppler indices
KW - Fetus
KW - Middle cerebral artery
UR - http://www.scopus.com/inward/record.url?scp=84975142522&partnerID=8YFLogxK
U2 - 10.1016/j.ijgo.2015.11.027
DO - 10.1016/j.ijgo.2015.11.027
M3 - Article
C2 - 27177520
AN - SCOPUS:84975142522
SN - 0020-7292
VL - 134
SP - 135
EP - 139
JO - International Journal of Gynecology and Obstetrics
JF - International Journal of Gynecology and Obstetrics
IS - 2
ER -