Fat may affect magnetic resonance signal intensity and brain tissue volumes

Anderson Mon; Christoph Abé; Timothy C. Durazzo; Dieter J. Meyerhoff

doi:10.1016/j.orcp.2015.07.009

Fat may affect magnetic resonance signal intensity and brain tissue volumes

Anderson Mon, Christoph Abé, Timothy C. Durazzo, Dieter J. Meyerhoff

Research output: Contribution to journal › Article › peer-review

8 Citations (Scopus)

Abstract

Obesity/overweight is reported to affect MR-measured brain tissue volume and white matter (WM) signal intensity. This study investigated possible effects of fat on these measures, using pig fat on three participants at a 4 T magnet. Grey matter volumes in the presence of fat were lower than baseline measures. Total WM volumes in the presence of fat were higher than baseline measures. WM hypo-intensities on T1-weighted images were higher in the presence of fat than baseline measures. Therefore physical effects of head fat of obese/overweight individual may at least, partly contribute to the association of obesity/overweight with MR structural measures.

Original language	English
Pages (from-to)	211-215
Number of pages	5
Journal	Obesity Research and Clinical Practice
Volume	10
Issue number	2
DOIs	https://doi.org/10.1016/j.orcp.2015.07.009
Publication status	Published - 1 Mar 2016
Externally published	Yes

Keywords

Fat
Grey matter
Magnetic resonance signal hypo-intensity
Obesity
White matter

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.orcp.2015.07.009

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title = "Fat may affect magnetic resonance signal intensity and brain tissue volumes",

abstract = "Obesity/overweight is reported to affect MR-measured brain tissue volume and white matter (WM) signal intensity. This study investigated possible effects of fat on these measures, using pig fat on three participants at a 4 T magnet. Grey matter volumes in the presence of fat were lower than baseline measures. Total WM volumes in the presence of fat were higher than baseline measures. WM hypo-intensities on T1-weighted images were higher in the presence of fat than baseline measures. Therefore physical effects of head fat of obese/overweight individual may at least, partly contribute to the association of obesity/overweight with MR structural measures.",

keywords = "Fat, Grey matter, Magnetic resonance signal hypo-intensity, Obesity, White matter",

author = "Anderson Mon and Christoph Ab{\'e} and Durazzo, \{Timothy C.\} and Meyerhoff, \{Dieter J.\}",

note = "Publisher Copyright: {\textcopyright} 2015 Asia Oceania Association for the Study of Obesity.",

year = "2016",

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doi = "10.1016/j.orcp.2015.07.009",

language = "English",

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journal = "Obesity Research and Clinical Practice",

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T1 - Fat may affect magnetic resonance signal intensity and brain tissue volumes

AU - Mon, Anderson

AU - Abé, Christoph

AU - Durazzo, Timothy C.

AU - Meyerhoff, Dieter J.

PY - 2016/3/1

Y1 - 2016/3/1

N2 - Obesity/overweight is reported to affect MR-measured brain tissue volume and white matter (WM) signal intensity. This study investigated possible effects of fat on these measures, using pig fat on three participants at a 4 T magnet. Grey matter volumes in the presence of fat were lower than baseline measures. Total WM volumes in the presence of fat were higher than baseline measures. WM hypo-intensities on T1-weighted images were higher in the presence of fat than baseline measures. Therefore physical effects of head fat of obese/overweight individual may at least, partly contribute to the association of obesity/overweight with MR structural measures.

AB - Obesity/overweight is reported to affect MR-measured brain tissue volume and white matter (WM) signal intensity. This study investigated possible effects of fat on these measures, using pig fat on three participants at a 4 T magnet. Grey matter volumes in the presence of fat were lower than baseline measures. Total WM volumes in the presence of fat were higher than baseline measures. WM hypo-intensities on T1-weighted images were higher in the presence of fat than baseline measures. Therefore physical effects of head fat of obese/overweight individual may at least, partly contribute to the association of obesity/overweight with MR structural measures.

KW - Fat

KW - Grey matter

KW - Magnetic resonance signal hypo-intensity

KW - Obesity

KW - White matter

UR - https://www.scopus.com/pages/publications/84938800518

U2 - 10.1016/j.orcp.2015.07.009

DO - 10.1016/j.orcp.2015.07.009

M3 - Article

C2 - 26259685

AN - SCOPUS:84938800518

SN - 1871-403X

VL - 10

SP - 211

EP - 215

JO - Obesity Research and Clinical Practice

JF - Obesity Research and Clinical Practice

IS - 2

ER -

Fat may affect magnetic resonance signal intensity and brain tissue volumes

Abstract

Keywords

UN SDGs

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