TY - JOUR
T1 - Factors associated with hypertension among stroke-free indigenous Africans
T2 - Findings from the SIREN study
AU - the SIREN Study as part of the H3Africa Consortium
AU - Akpa, Onoja M.
AU - Okekunle, Akinkunmi P.
AU - Ovbiagele, Bruce
AU - Sarfo, Fred S.
AU - Akinyemi, Rufus O.
AU - Akpalu, Albert
AU - Wahab, Kolawole W.
AU - Komolafe, Morenikeji
AU - Obiako, Reginald
AU - Owolabi, Lukman F.
AU - Ogbole, Godwin
AU - Fawale, Bimbo
AU - Fakunle, Adekunle
AU - Asaleye, Christianah M.
AU - Akisanya, Cynthia O.
AU - Hamisu, Dambatta A.
AU - Ogunjimi, Luqman
AU - Adeoye, Abiodun
AU - Ogah, Okechukwu
AU - Lackland, Dan
AU - Uvere, Ezinne O.
AU - Faniyan, Moyinoluwalogo M.
AU - Asowata, Osahon J.
AU - Adeleye, Osimhiarherhuo
AU - Aridegbe, Mayowa
AU - Olunuga, Taiwo
AU - Yahaya, Isah S.
AU - Olaleye, Adeniji
AU - Calys-Tagoe, Benedict
AU - Owolabi, Mayowa O.
N1 - Publisher Copyright:
© 2021 The Authors. The Journal of Clinical Hypertension published by Wiley Periodicals LLC.
PY - 2021/4
Y1 - 2021/4
N2 - Hypertension is one of the most important risk factors for stroke and cardiovascular diseases (CVD) globally. Understanding risk factors for hypertension among individuals with matching characteristics with stroke patients may inform primordial/primary prevention of hypertension and stroke among them. This study identified the risk factors for hypertension among community-dwelling stroke-free population in Ghana and Nigeria. Data for 4267 community-dwelling stroke-free controls subjects in the Stroke Investigative Research and Education Network (SIREN) study in Nigeria and Ghana were used. Participants were comprehensively assessed for sociodemographic, lifestyle and metabolic factors using standard methods. Hypertension was defined as a previous diagnosis by a health professional or use of an anti-hypertensive drug or mean systolic blood pressure ≥ 140 mmHg and/or diastolic blood pressure ≥ 90 mmHg. Logistic regression analysis was used to estimate adjusted odds ratios (aOR) of hypertension and their 95% confidence intervals (CI) at p <.05. Overall, 56.7% of the participants were hypertensive with a higher proportion among respondents aged ≥60 years (53.0%). Factors including physical inactivity (aOR: 9.09; 95% CI: 4.03 to 20.53, p <.0001), diabetes (aOR: 2.70; CI: 1.91 to 3.82, p <.0001), being ≥60 years (aOR: 2.22; 95% CI: 1.78 to 2.77, p <.0001), and family history of CVD (aOR 2.02; CI: 1.59 to 2.56, p <.0001) were associated with increased aOR of hypertension. Lifestyle factors were associated with hypertension in the current population of community-dwelling stroke-free controls in west Africa. Community-oriented interventions to address sedentary lifestyles may benefit this population and reduce/prevent hypertension and stroke among them.
AB - Hypertension is one of the most important risk factors for stroke and cardiovascular diseases (CVD) globally. Understanding risk factors for hypertension among individuals with matching characteristics with stroke patients may inform primordial/primary prevention of hypertension and stroke among them. This study identified the risk factors for hypertension among community-dwelling stroke-free population in Ghana and Nigeria. Data for 4267 community-dwelling stroke-free controls subjects in the Stroke Investigative Research and Education Network (SIREN) study in Nigeria and Ghana were used. Participants were comprehensively assessed for sociodemographic, lifestyle and metabolic factors using standard methods. Hypertension was defined as a previous diagnosis by a health professional or use of an anti-hypertensive drug or mean systolic blood pressure ≥ 140 mmHg and/or diastolic blood pressure ≥ 90 mmHg. Logistic regression analysis was used to estimate adjusted odds ratios (aOR) of hypertension and their 95% confidence intervals (CI) at p <.05. Overall, 56.7% of the participants were hypertensive with a higher proportion among respondents aged ≥60 years (53.0%). Factors including physical inactivity (aOR: 9.09; 95% CI: 4.03 to 20.53, p <.0001), diabetes (aOR: 2.70; CI: 1.91 to 3.82, p <.0001), being ≥60 years (aOR: 2.22; 95% CI: 1.78 to 2.77, p <.0001), and family history of CVD (aOR 2.02; CI: 1.59 to 2.56, p <.0001) were associated with increased aOR of hypertension. Lifestyle factors were associated with hypertension in the current population of community-dwelling stroke-free controls in west Africa. Community-oriented interventions to address sedentary lifestyles may benefit this population and reduce/prevent hypertension and stroke among them.
KW - Sub-Saharan Africa
KW - hypertension
KW - physical inactivity
KW - risk factors
UR - http://www.scopus.com/inward/record.url?scp=85099821783&partnerID=8YFLogxK
U2 - 10.1111/jch.14183
DO - 10.1111/jch.14183
M3 - Article
C2 - 33484599
AN - SCOPUS:85099821783
SN - 1524-6175
VL - 23
SP - 773
EP - 784
JO - Journal of Clinical Hypertension
JF - Journal of Clinical Hypertension
IS - 4
ER -