TY - JOUR
T1 - Factors associated with adverse obstetric events following induction of labour
T2 - a retrospective study in a tertiary hospital in Ghana
AU - Adu-Bonsaffoh, Kwame
AU - Seffah, Joseph
N1 - Publisher Copyright:
© 2022 Adu-Bonsaffoh K et al. Licensee African Health Sciences.
PY - 2022
Y1 - 2022
N2 - Background: Induction of labour (IOL) remains an indispensable intervention in obstetric practice; however, it may be associated with significant untoward perinatal outcomes. This study determined the major adverse outcomes of IOL and the associated factors at a tertiary hospital in Ghana Methods: Retrospective study involving women with singleton gestations, conducted at the Korle Teaching Hospital in Ghana. Multivariable logistic regression was used to explore the factors associated with adverse outcomes of IOL. Findings: A total of 195 women who had IOL were analysed with 161 (82.6%) and 34 (17.4%) undergoing vaginal and caesarean deliveries respectively. The main IOL methods used included Misoprostol (91.3%), Oxytocin (5.1%) and Foley’s catheter (3.6%). Composite adverse perinatal outcomes occurred in 46 neonates (23.6%) comprising perinatal deaths (7.2%) and or NICU admission (21.0%). Caesarean delivery following IOL was significantly associated with nulliparity, gestational age <41 weeks, hypertensive disorders in pregnancy and birth weight ≥3.5kg. Gestational age <41 weeks and birth weight <2.5kg were significantly associated with adverse perinatal outcome. Five women (2.6%) had uterine rupture all of which occurred in the misoprostol group. Conclusion: Induction of labour may result in significant perinatal complications which are related to both maternal (nullipar-ity and hypertension) and fetal (gestational age and birth weight) factors. Strict selection criteria and continuous fetal-maternal monitoring are strongly recommended to improve the birth outcomes of IOL.
AB - Background: Induction of labour (IOL) remains an indispensable intervention in obstetric practice; however, it may be associated with significant untoward perinatal outcomes. This study determined the major adverse outcomes of IOL and the associated factors at a tertiary hospital in Ghana Methods: Retrospective study involving women with singleton gestations, conducted at the Korle Teaching Hospital in Ghana. Multivariable logistic regression was used to explore the factors associated with adverse outcomes of IOL. Findings: A total of 195 women who had IOL were analysed with 161 (82.6%) and 34 (17.4%) undergoing vaginal and caesarean deliveries respectively. The main IOL methods used included Misoprostol (91.3%), Oxytocin (5.1%) and Foley’s catheter (3.6%). Composite adverse perinatal outcomes occurred in 46 neonates (23.6%) comprising perinatal deaths (7.2%) and or NICU admission (21.0%). Caesarean delivery following IOL was significantly associated with nulliparity, gestational age <41 weeks, hypertensive disorders in pregnancy and birth weight ≥3.5kg. Gestational age <41 weeks and birth weight <2.5kg were significantly associated with adverse perinatal outcome. Five women (2.6%) had uterine rupture all of which occurred in the misoprostol group. Conclusion: Induction of labour may result in significant perinatal complications which are related to both maternal (nullipar-ity and hypertension) and fetal (gestational age and birth weight) factors. Strict selection criteria and continuous fetal-maternal monitoring are strongly recommended to improve the birth outcomes of IOL.
KW - Ghana
KW - Induction of labour
KW - adverse outcomes
UR - http://www.scopus.com/inward/record.url?scp=85145189030&partnerID=8YFLogxK
U2 - 10.4314/ahs.v22i4.40
DO - 10.4314/ahs.v22i4.40
M3 - Article
C2 - 37092103
AN - SCOPUS:85145189030
SN - 1680-6905
VL - 22
SP - 348
EP - 356
JO - African Health Sciences
JF - African Health Sciences
IS - 4
ER -