Effect of the Newhints home-visits intervention on neonatal mortality rate and care practices in Ghana: A cluster randomised controlled trial

Betty R. Kirkwood, Alexander Manu, Augustinus H.A. Ten Asbroek, Seyi Soremekun, Benedict Weobong, Thomas Gyan, Samuel Danso, Seeba Amenga-Etego, Charlotte Tawiah-Agyemang, Seth Owusu-Agyei, Zelee Hill

Research output: Contribution to journalArticlepeer-review

153 Citations (Scopus)

Abstract

Background In 2009, on the basis of promising evidence from trials in south Asia, WHO and UNICEF issued a joint statement about home visits as a strategy to improve newborn survival. In the Newhints trial, we aimed to test this home-visits strategy in sub-Saharan Africa by assessing the Effect on all-cause neonatal mortality rate (NMR) and essential newborn-care practices. Methods The Newhints cluster randomised trial was undertaken in 98 zones in seven districts in the Brong Ahafo Region, Ghana. 49 zones were randomly assigned to the Newhints intervention and 49 to the control intervention by use of restricted randomisation with stratifi cation to ensure comparability between interventions. Community-based surveillance volunteers (CBSVs) in Newhints zones were trained to identify pregnant women in their community and to make two home visits during pregnancy and three in the fi rst week of life to promote essential newborn-care practices, weigh and assess babies for danger signs, and refer as necessary. Primary outcomes were NMR and coverage of key essential newborn-care practices. Analyses were by intention to treat. This study is registered with ClinicalTrials.gov, number NCT00623337.

Original languageEnglish
Pages (from-to)2184-2192
Number of pages9
JournalThe Lancet
Volume381
Issue number9884
DOIs
Publication statusPublished - 2013
Externally publishedYes

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