Do alterations in inter-ictal heart rate variability predict sudden unexpected death in epilepsy?

R. Surges, C. Henneberger, P. Adjei, C. A. Scott, J. W. Sander, M. C. Walker

Research output: Contribution to journalArticlepeer-review

69 Citations (Scopus)

Abstract

Reduced heart rate variability (HRV) may predispose to sudden unexpected death in epilepsy (SUDEP). We ascertained whether HRV predicts SUDEP in chronic epilepsy using a case-control design and investigated parameters of inter-ictal HRV in 14 patients (7 had died from SUDEP). No HRV parameter was associated with SUDEP. Thus, although altered HRV might be involved in SUDEP, HRV parameters are not clear-cut predictors for SUDEP.

Original languageEnglish
Pages (from-to)277-280
Number of pages4
JournalEpilepsy Research
Volume87
Issue number2-3
DOIs
Publication statusPublished - Dec 2009
Externally publishedYes

Keywords

  • Autonomic dysfunction
  • Heart rate variability
  • Nocturnal seizures
  • Sudden unexpected death in epilepsy
  • Sympathetic tone

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