TY - JOUR
T1 - Dietary patterns associated with stroke among West Africans
T2 - A case–control study
AU - Okekunle, Akinkunmi P.
AU - Asowata, Osahon
AU - Akpa, Onoja M.
AU - Ovbiagele, Bruce
AU - Fakunle, Adekunle
AU - Komolafe, Morenikeji
AU - Arulogun, Oyedunni
AU - Sarfo, Fred S.
AU - Akpalu, Albert
AU - Obiako, Reginald
AU - Wahab, Kolawole
AU - Osaigbovo, Godwin
AU - Owolabi, Lukman
AU - Ogbole, Godwin
AU - Akinyemi, Joshua
AU - Adeniyi, Sunday
AU - Calys-Tagoe, Benedict
AU - Aridegbe, Mayowa
AU - Adebowale, Akintunde
AU - Dambatta, Hamisu
AU - Agunloye, Atinuke
AU - Oyinloye, Olalekan
AU - Aderibigbe, Adeniyi
AU - Suleiman, Isah
AU - Adeoye, Abiodun M.
AU - Akpalu, Josephine
AU - Agbogu-Ike, Obiageli
AU - Tiwari, Hemant K.
AU - Arnett, Donna
AU - Akinyemi, Rufus
AU - Owolabi, Mayowa O.
N1 - Publisher Copyright:
© 2022 World Stroke Organization.
PY - 2023/2
Y1 - 2023/2
N2 - Background: The relationship of diet with stroke risk among Africans is not well understood. Aim: The aim of this study was to investigate the association between dietary patterns and stroke risk among West Africans. Methods: In this multi-center case–control study, 3684 stroke patients matched (for age and sex) with 3684 healthy controls were recruited from Nigeria and Ghana. Food consumption was assessed using a food frequency questionnaire, and dietary patterns were summarized using principal component analysis. Stroke was defined using predefined criteria primarily on clinical evaluation following standard guidelines. Conditional logistic regression was applied to compute odds ratio (OR) and 95% confidence interval (CI) for stroke risk by tertiles of dietary patterns adjusting for relevant confounders. Results: Overall, mean age was 59.0 ± 13.9 years, and 3992 (54.2%) were males. Seven dietary patterns were identified. Multivariable-adjusted OR (95% CI) for risk of stroke by second and third tertiles (using the lowest and first tertile as reference) of dietary patterns was 1.65 (1.43, 1.90) and 1.74 (1.51, 2.02), for “poultry product and organ meat”; 1.69 (1.47, 1.96) and 1.51 (1.31, 1.75) for “red meat”; 1.07 (0.92, 1.23) and 1.21 (1.04, 1.40) for “fried foods and sweetened drinks”; 0.69 (0.60, 0.80) and 0.45 (0.39, 0.53) for “vegetables”; 0.84 (0.72, 0.97) and 0.81 (0.70, 0.93) for “whole-grain and fruit drinks”; and 0.97 (0.84, 1.12) and 0.85 (0.73, 0.98) for “fruits” respectively (p < 0.05). Conclusion: These data suggest that plant-based diets are associated with a lower risk of stroke and might be a beneficial dietary recommendation for the primary prevention of stroke among Africans.
AB - Background: The relationship of diet with stroke risk among Africans is not well understood. Aim: The aim of this study was to investigate the association between dietary patterns and stroke risk among West Africans. Methods: In this multi-center case–control study, 3684 stroke patients matched (for age and sex) with 3684 healthy controls were recruited from Nigeria and Ghana. Food consumption was assessed using a food frequency questionnaire, and dietary patterns were summarized using principal component analysis. Stroke was defined using predefined criteria primarily on clinical evaluation following standard guidelines. Conditional logistic regression was applied to compute odds ratio (OR) and 95% confidence interval (CI) for stroke risk by tertiles of dietary patterns adjusting for relevant confounders. Results: Overall, mean age was 59.0 ± 13.9 years, and 3992 (54.2%) were males. Seven dietary patterns were identified. Multivariable-adjusted OR (95% CI) for risk of stroke by second and third tertiles (using the lowest and first tertile as reference) of dietary patterns was 1.65 (1.43, 1.90) and 1.74 (1.51, 2.02), for “poultry product and organ meat”; 1.69 (1.47, 1.96) and 1.51 (1.31, 1.75) for “red meat”; 1.07 (0.92, 1.23) and 1.21 (1.04, 1.40) for “fried foods and sweetened drinks”; 0.69 (0.60, 0.80) and 0.45 (0.39, 0.53) for “vegetables”; 0.84 (0.72, 0.97) and 0.81 (0.70, 0.93) for “whole-grain and fruit drinks”; and 0.97 (0.84, 1.12) and 0.85 (0.73, 0.98) for “fruits” respectively (p < 0.05). Conclusion: These data suggest that plant-based diets are associated with a lower risk of stroke and might be a beneficial dietary recommendation for the primary prevention of stroke among Africans.
KW - Diet
KW - West Africans
KW - principal component analysis
KW - stroke
UR - http://www.scopus.com/inward/record.url?scp=85130451749&partnerID=8YFLogxK
U2 - 10.1177/17474930221094933
DO - 10.1177/17474930221094933
M3 - Article
C2 - 35377255
AN - SCOPUS:85130451749
SN - 1747-4930
VL - 18
SP - 193
EP - 200
JO - International Journal of Stroke
JF - International Journal of Stroke
IS - 2
ER -