TY - JOUR
T1 - Contributions and challenges for worldwide vaccine safety
T2 - The Global Advisory Committee on Vaccine Safety at 15 years
AU - Asturias, Edwin J.
AU - Wharton, Melinda
AU - Pless, Robert
AU - MacDonald, Noni E.
AU - Chen, Robert T.
AU - Andrews, Nicholas
AU - Salisbury, David
AU - Dodoo, Alexander N.
AU - Hartigan-Go, Kenneth
AU - Zuber, Patrick L.F.
N1 - Publisher Copyright:
© 2016 Elsevier Ltd
PY - 2016/6/17
Y1 - 2016/6/17
N2 - In 1999, the Global Advisory Committee on Vaccine Safety (GACVS) was established by the World Health Organization (WHO) to provide independent scientific advice on issues relating to the safety of vaccines and immunization. Fifteen years onward, we conducted a multi-faceted review to evaluate the impact, reach and challenges facing GACVS, including the role GACVS plays in informing global, regional and WHO member state vaccine policy. The methods included measures of organizational structure, citation impact, themes approached, and a discussion by previous and current members to evaluate past, present and future challenges. Given the increasing range of data sources and the deployment of many new vaccines, the Committee is facing the complex task of identifying the best available evidence for recommendations on vaccine safety. To help meet the increased demand for public transparency in decision making, GACVS-structured methodology for evidence-based decisions is evolving. GACVS also promotes best practices and capacity building for timely and accurate risk assessment; risk communications; outreach to help countries maintain and, if needed, rebuild public trust in vaccines; and advocacy for bridging the major gaps in vaccine safety capacity globally.
AB - In 1999, the Global Advisory Committee on Vaccine Safety (GACVS) was established by the World Health Organization (WHO) to provide independent scientific advice on issues relating to the safety of vaccines and immunization. Fifteen years onward, we conducted a multi-faceted review to evaluate the impact, reach and challenges facing GACVS, including the role GACVS plays in informing global, regional and WHO member state vaccine policy. The methods included measures of organizational structure, citation impact, themes approached, and a discussion by previous and current members to evaluate past, present and future challenges. Given the increasing range of data sources and the deployment of many new vaccines, the Committee is facing the complex task of identifying the best available evidence for recommendations on vaccine safety. To help meet the increased demand for public transparency in decision making, GACVS-structured methodology for evidence-based decisions is evolving. GACVS also promotes best practices and capacity building for timely and accurate risk assessment; risk communications; outreach to help countries maintain and, if needed, rebuild public trust in vaccines; and advocacy for bridging the major gaps in vaccine safety capacity globally.
KW - Global Advisory Committee on Vaccine Safety
KW - Global public health
KW - Immunization program
KW - Vaccine adverse events
KW - Vaccine policy
KW - Vaccine safety
UR - http://www.scopus.com/inward/record.url?scp=84969560226&partnerID=8YFLogxK
U2 - 10.1016/j.vaccine.2016.05.018
DO - 10.1016/j.vaccine.2016.05.018
M3 - Article
C2 - 27195758
AN - SCOPUS:84969560226
SN - 0264-410X
VL - 34
SP - 3342
EP - 3349
JO - Vaccine
JF - Vaccine
IS - 29
ER -