@article{50f8baf489634e73a46b2d4a0d896191,
title = "Circulating tumor DNA is readily detectable among Ghanaian breast cancer patients supporting non-invasive cancer genomic studies in Africa",
abstract = "Circulating tumor DNA (ctDNA) sequencing studies could provide novel insights into the molecular pathology of cancer in sub-Saharan Africa. In 15 patient plasma samples collected at the time of diagnosis as part of the Ghana Breast Health Study and unselected for tumor grade and subtype, ctDNA was detected in a majority of patients based on whole- genome sequencing at high (30×) and low (0.1×) depths. Breast cancer driver copy number alterations were observed in the majority of patients.",
author = "{the Ghana Breast Health Study Team} and Ahuno, {Samuel Terkper} and Doebley, {Anna Lisa} and Ahearn, {Thomas U.} and Joel Yarney and Nicholas Titiloye and Nancy Hamel and Ernest Adjei and Clegg-Lamptey, {Joe Nat} and Lawrence Edusei and Baffour Awuah and Xiaoyu Song and Verna Vanderpuye and Mustapha Abubakar and Maire Duggan and Stover, {Daniel G.} and Kofi Nyarko and Bartlett, {John M.S.} and Francis Aitpillah and Daniel Ansong and Gardner, {Kevin L.} and Boateng, {Felix Andy} and Bowcock, {Anne M.} and Carlos Caldas and Foulkes, {William D.} and Seth Wiafe and Beatrice Wiafe-Addai and Montserrat Garcia-Closas and Alexander Kwarteng and Gavin Ha and Figueroa, {Jonine D.} and Paz Polak and Robertson Adjei and Lucy Afriyie and Anthony Adjei and Florence Dedey and Victoria Okyne and Oti, {Naomi Ohene} and Evelyn Tay and Adu-Aryee and Angela Kenu and Obed Ekpedzor and Marion Alcpaloo and Isaac Boakye and Bernard Arhin and Emmanuel Assimah and Samuel Ka-Chungu and Joseph Oppong and Ernest Osei-Bonsu and Margaret Frempong and Abaidoo, {Emma Brew}",
note = "Publisher Copyright: {\textcopyright} 2021, The Author(s).",
year = "2021",
month = dec,
doi = "10.1038/s41698-021-00219-7",
language = "English",
volume = "5",
journal = "npj Precision Oncology",
issn = "2397-768X",
publisher = "Springer Nature",
number = "1",
}