TY - JOUR
T1 - Characterization of staphylococcus aureus from human immunodeficiency virus (HIV) patients in Accra, Ghana
AU - Egyir, Beverly
AU - Oteng, Akwasi Ampofo
AU - Owusu, Enid
AU - Newman, Mercy Jemimah
AU - Addo, Kennedy Kwasi
AU - Larsen, Anders Rhod
N1 - Publisher Copyright:
© 2016 Egyir et al.
PY - 2016/5
Y1 - 2016/5
N2 - Introduction: The aims of this study were to: a) determine the nasal carriage prevalence of Stahpylococcus aureus among HIV patients, b) to characterize S. aureus strains isolated. Methodology: Characterization of S. aureus isolates was done by antibiotyping, spa typing, and detection of Panton-Valentine leukocidin (PVL) genes. Results: S. aureus isolated (10/124; 8%) belonged to spa types t084 (n = 3), t10828 (n = 2), t311, t304, t774, t645, and t091. The isolates were resistant to penicillin (100%), tetracycline (40%), rifampicin (10%), fucidic acid (10%), norfloxacin (10%), erythromycin (10%), and sulfamethoxazole trimethoprim (10%). Multidrug resistance (MDR) was detected in 30% of the isolates. Conclusion: The finding of MDR S. aureus among HIV-positive patients suggests that surveillance of antimicrobial resistant S. aureus among this patient group could be considered as an infection control measure in the hospital.
AB - Introduction: The aims of this study were to: a) determine the nasal carriage prevalence of Stahpylococcus aureus among HIV patients, b) to characterize S. aureus strains isolated. Methodology: Characterization of S. aureus isolates was done by antibiotyping, spa typing, and detection of Panton-Valentine leukocidin (PVL) genes. Results: S. aureus isolated (10/124; 8%) belonged to spa types t084 (n = 3), t10828 (n = 2), t311, t304, t774, t645, and t091. The isolates were resistant to penicillin (100%), tetracycline (40%), rifampicin (10%), fucidic acid (10%), norfloxacin (10%), erythromycin (10%), and sulfamethoxazole trimethoprim (10%). Multidrug resistance (MDR) was detected in 30% of the isolates. Conclusion: The finding of MDR S. aureus among HIV-positive patients suggests that surveillance of antimicrobial resistant S. aureus among this patient group could be considered as an infection control measure in the hospital.
KW - Africa
KW - HIV patients
KW - Nasal carriage
KW - Staphylococcus aureus
UR - https://www.scopus.com/pages/publications/84971451886
U2 - 10.3855/jidc.7428
DO - 10.3855/jidc.7428
M3 - Article
C2 - 27249519
AN - SCOPUS:84971451886
SN - 2036-6590
VL - 10
SP - 453
EP - 456
JO - Journal of Infection in Developing Countries
JF - Journal of Infection in Developing Countries
IS - 5
ER -
