TY - JOUR
T1 - CHANGES IN SERUM ELECTROLYTES IN BLOOD TRANSFUSED AND NON-TRANSFUSED POST-OPERATIVE PATIENTS AT A NATIONAL REFERRAL HOSPITAL IN GHANA
AU - Yawson, A. O.
AU - Antwi-Boasiako, C.
AU - Djagbletey, R.
AU - Abindau, E.
AU - Aheto, J. M.K.
AU - Botchway, F. A.
AU - Adepa, F. E.
AU - Yawson, A. E.
N1 - Publisher Copyright:
© 2021, Ghana College of Physicians and Surgeons. All rights reserved.
PY - 2021
Y1 - 2021
N2 - Background: Red blood cell transfusion among patients is an essential part of medical care, and can be life-sav-ing. This study therefore determined changes in serum electrolyte in blood transfused and non-transfused post-operative patients at the Korle-Bu Teaching Hospital (KBTH) in Ghana. Methodology: This was a hospital-based longitudinal study involving 160 female patients aged 18-70 years admitted to the KBTH and screened pre-operatively. In all 92 general surgical and gynaecological adult patients who met the inclusion criteria were studied post-post operatively. Data abstraction form was used for data collection on demographic, weight and serum electrolytes. Categorical data were analysed using chi-square. Independent t-test was used to compare the means for the two groups, while the paired t-test was used to compare the means for the immediate post-operative and 24 hours post-operative period, using SPSS version 23.0 software. Results: In the transfused patients, serum levels of sodium (p= 0.297), Chloride (p= 0.143), and calcium (p= 0.368) increased, while potassium (p= 0.383) and magnesium (p= 0.147) levels decreased after transfusion; although not statistically significant. However, there was a significant decrease in serum levels of sodium (p= 0.040), potassium (p= 0.001), and magnesium (p= 0.026) in non-transfused patients 24 hours post operatively. Hypomagnesemia was observed among the transfused patients in this study (pre-transfusion, 0.66±0.05 vs. post transfusion, 0.57±0.04, p= 0.147) Conclusion: Blood transfusion corrected serum electrolyte levels in patients after surgery. Serum electrolytes monitoring is clinically useful in post-operative patients in this large referral hospital.
AB - Background: Red blood cell transfusion among patients is an essential part of medical care, and can be life-sav-ing. This study therefore determined changes in serum electrolyte in blood transfused and non-transfused post-operative patients at the Korle-Bu Teaching Hospital (KBTH) in Ghana. Methodology: This was a hospital-based longitudinal study involving 160 female patients aged 18-70 years admitted to the KBTH and screened pre-operatively. In all 92 general surgical and gynaecological adult patients who met the inclusion criteria were studied post-post operatively. Data abstraction form was used for data collection on demographic, weight and serum electrolytes. Categorical data were analysed using chi-square. Independent t-test was used to compare the means for the two groups, while the paired t-test was used to compare the means for the immediate post-operative and 24 hours post-operative period, using SPSS version 23.0 software. Results: In the transfused patients, serum levels of sodium (p= 0.297), Chloride (p= 0.143), and calcium (p= 0.368) increased, while potassium (p= 0.383) and magnesium (p= 0.147) levels decreased after transfusion; although not statistically significant. However, there was a significant decrease in serum levels of sodium (p= 0.040), potassium (p= 0.001), and magnesium (p= 0.026) in non-transfused patients 24 hours post operatively. Hypomagnesemia was observed among the transfused patients in this study (pre-transfusion, 0.66±0.05 vs. post transfusion, 0.57±0.04, p= 0.147) Conclusion: Blood transfusion corrected serum electrolyte levels in patients after surgery. Serum electrolytes monitoring is clinically useful in post-operative patients in this large referral hospital.
KW - adult surgical patients
KW - blood transfusion
KW - post-operative period
KW - serum electrolytes
KW - Sub-Saharan Africa
UR - http://www.scopus.com/inward/record.url?scp=85189345501&partnerID=8YFLogxK
U2 - 10.60014/pmjg.v10i1.245
DO - 10.60014/pmjg.v10i1.245
M3 - Article
AN - SCOPUS:85189345501
SN - 2026-6790
VL - 10
SP - 5
EP - 13
JO - Postgraduate Medical Journal of Ghana
JF - Postgraduate Medical Journal of Ghana
IS - 1
ER -