Carriage of diarrhoeagenic Escherichia coli by older children and adults in Accra, Ghana

Japheth A. Opintan; Rima A. Bishar; Mercy J. Newman; Iruka N. Okeke

doi:10.1016/j.trstmh.2010.02.011

Carriage of diarrhoeagenic Escherichia coli by older children and adults in Accra, Ghana

Japheth A. Opintan
, Rima A. Bishar
, Mercy J. Newman
, Iruka N. Okeke

Department of Medical Microbiology

Haverford College
University of Ghana

Research output: Contribution to journal › Article › peer-review

23 Citations (Scopus)

Abstract

Diarrhoeagenic Escherichia coli (DEC) were sought in stool specimens from 72 adults and children aged over 3 years, who presented with diarrhoea at a hospital in Accra, Ghana, and 72 matched controls. Only diffusely-adherent E. coli were significantly associated with disease in these older individuals (P=0.029). We additionally tested 53 specimens from infants among whom DEC were collectively associated with disease (P=0.012). Enteropathogenic, enterotoxigenic and enteroaggregative E. coli, the most commonly isolated pathotypes from infants with diarrhoea, were frequently recovered from healthy adults. Asymptomatic carriage of DEC by older individuals in Accra may place young children at risk for diarrhoea.

Original language	English
Pages (from-to)	504-506
Number of pages	3
Journal	Transactions of the Royal Society of Tropical Medicine and Hygiene
Volume	104
Issue number	7
DOIs	https://doi.org/10.1016/j.trstmh.2010.02.011
Publication status	Published - Jul 2010

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Diarrhoea
Diffusely-adherent Escherichia coli
Enteroaggregative Escherichia coli
Enteropathogenic Escherichia coli
Enterotoxigenic Escherichia coli
Escherichia coli
Ghana

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10.1016/j.trstmh.2010.02.011

Cite this

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title = "Carriage of diarrhoeagenic Escherichia coli by older children and adults in Accra, Ghana",

abstract = "Diarrhoeagenic Escherichia coli (DEC) were sought in stool specimens from 72 adults and children aged over 3 years, who presented with diarrhoea at a hospital in Accra, Ghana, and 72 matched controls. Only diffusely-adherent E. coli were significantly associated with disease in these older individuals (P=0.029). We additionally tested 53 specimens from infants among whom DEC were collectively associated with disease (P=0.012). Enteropathogenic, enterotoxigenic and enteroaggregative E. coli, the most commonly isolated pathotypes from infants with diarrhoea, were frequently recovered from healthy adults. Asymptomatic carriage of DEC by older individuals in Accra may place young children at risk for diarrhoea.",

keywords = "Diarrhoea, Diffusely-adherent Escherichia coli, Enteroaggregative Escherichia coli, Enteropathogenic Escherichia coli, Enterotoxigenic Escherichia coli, Escherichia coli, Ghana",

author = "Opintan, \{Japheth A.\} and Bishar, \{Rima A.\} and Newman, \{Mercy J.\} and Okeke, \{Iruka N.\}",

year = "2010",

month = jul,

doi = "10.1016/j.trstmh.2010.02.011",

language = "English",

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journal = "Transactions of the Royal Society of Tropical Medicine and Hygiene",

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}

TY - JOUR

T1 - Carriage of diarrhoeagenic Escherichia coli by older children and adults in Accra, Ghana

AU - Opintan, Japheth A.

AU - Bishar, Rima A.

AU - Newman, Mercy J.

AU - Okeke, Iruka N.

PY - 2010/7

Y1 - 2010/7

N2 - Diarrhoeagenic Escherichia coli (DEC) were sought in stool specimens from 72 adults and children aged over 3 years, who presented with diarrhoea at a hospital in Accra, Ghana, and 72 matched controls. Only diffusely-adherent E. coli were significantly associated with disease in these older individuals (P=0.029). We additionally tested 53 specimens from infants among whom DEC were collectively associated with disease (P=0.012). Enteropathogenic, enterotoxigenic and enteroaggregative E. coli, the most commonly isolated pathotypes from infants with diarrhoea, were frequently recovered from healthy adults. Asymptomatic carriage of DEC by older individuals in Accra may place young children at risk for diarrhoea.

AB - Diarrhoeagenic Escherichia coli (DEC) were sought in stool specimens from 72 adults and children aged over 3 years, who presented with diarrhoea at a hospital in Accra, Ghana, and 72 matched controls. Only diffusely-adherent E. coli were significantly associated with disease in these older individuals (P=0.029). We additionally tested 53 specimens from infants among whom DEC were collectively associated with disease (P=0.012). Enteropathogenic, enterotoxigenic and enteroaggregative E. coli, the most commonly isolated pathotypes from infants with diarrhoea, were frequently recovered from healthy adults. Asymptomatic carriage of DEC by older individuals in Accra may place young children at risk for diarrhoea.

KW - Diarrhoea

KW - Diffusely-adherent Escherichia coli

KW - Enteroaggregative Escherichia coli

KW - Enteropathogenic Escherichia coli

KW - Enterotoxigenic Escherichia coli

KW - Escherichia coli

KW - Ghana

UR - https://www.scopus.com/pages/publications/77954218877

U2 - 10.1016/j.trstmh.2010.02.011

DO - 10.1016/j.trstmh.2010.02.011

M3 - Article

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AN - SCOPUS:77954218877

SN - 0035-9203

VL - 104

SP - 504

EP - 506

JO - Transactions of the Royal Society of Tropical Medicine and Hygiene

JF - Transactions of the Royal Society of Tropical Medicine and Hygiene

IS - 7

ER -

Carriage of diarrhoeagenic Escherichia coli by older children and adults in Accra, Ghana

Abstract

UN SDGs

Keywords

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