Carbapenem Resistance: A Review

Francis S. Codjoe; Eric S. Donkor

doi:10.3390/medsci6010001

Carbapenem Resistance: A Review

Francis S. Codjoe
, Eric S. Donkor

Department of Medical Microbiology

University of Ghana
Sheffield Hallam University

Research output: Contribution to journal › Review article › peer-review

579 Citations (Scopus)

Abstract

Carbapenem resistance is a major and an on-going public health problem globally. It occurs mainly among Gram-negative pathogens such as Klebsiella pneumoniae, Pseudomonas aeruginosa and Acinetobacter baumannii, and may be intrinsic or mediated by transferable carbapenemase-encoding genes. This type of resistance genes are already widespread in certain parts of the world, particularly Europe, Asia and South America, while the situation in other places such as sub-Saharan Africa is not well documented. In this paper, we provide an in-depth review of carbapenem resistance providing up-to-date information on the subject.

Original language	English
Journal	Medical sciences (Basel, Switzerland)
Volume	6
Issue number	1
DOIs	https://doi.org/10.3390/medsci6010001
Publication status	Published - 21 Dec 2017

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Gram negative bacilli
antibiotic resistance
carbapenemases
carbapenems

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10.3390/medsci6010001

Cite this

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AU - Donkor, Eric S.

PY - 2017/12/21

Y1 - 2017/12/21

N2 - Carbapenem resistance is a major and an on-going public health problem globally. It occurs mainly among Gram-negative pathogens such as Klebsiella pneumoniae, Pseudomonas aeruginosa and Acinetobacter baumannii, and may be intrinsic or mediated by transferable carbapenemase-encoding genes. This type of resistance genes are already widespread in certain parts of the world, particularly Europe, Asia and South America, while the situation in other places such as sub-Saharan Africa is not well documented. In this paper, we provide an in-depth review of carbapenem resistance providing up-to-date information on the subject.

AB - Carbapenem resistance is a major and an on-going public health problem globally. It occurs mainly among Gram-negative pathogens such as Klebsiella pneumoniae, Pseudomonas aeruginosa and Acinetobacter baumannii, and may be intrinsic or mediated by transferable carbapenemase-encoding genes. This type of resistance genes are already widespread in certain parts of the world, particularly Europe, Asia and South America, while the situation in other places such as sub-Saharan Africa is not well documented. In this paper, we provide an in-depth review of carbapenem resistance providing up-to-date information on the subject.

KW - Gram negative bacilli

KW - antibiotic resistance

KW - carbapenemases

KW - carbapenems

UR - https://www.scopus.com/pages/publications/85149152938

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JO - Medical sciences (Basel, Switzerland)

JF - Medical sciences (Basel, Switzerland)

IS - 1

ER -

Carbapenem Resistance: A Review

Abstract

UN SDGs

Keywords

Access to Document

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