TY - JOUR
T1 - Carbapenem Resistance
T2 - A Review
AU - Codjoe, Francis S.
AU - Donkor, Eric S.
PY - 2017/12/21
Y1 - 2017/12/21
N2 - Carbapenem resistance is a major and an on-going public health problem globally. It occurs mainly among Gram-negative pathogens such as Klebsiella pneumoniae, Pseudomonas aeruginosa and Acinetobacter baumannii, and may be intrinsic or mediated by transferable carbapenemase-encoding genes. This type of resistance genes are already widespread in certain parts of the world, particularly Europe, Asia and South America, while the situation in other places such as sub-Saharan Africa is not well documented. In this paper, we provide an in-depth review of carbapenem resistance providing up-to-date information on the subject.
AB - Carbapenem resistance is a major and an on-going public health problem globally. It occurs mainly among Gram-negative pathogens such as Klebsiella pneumoniae, Pseudomonas aeruginosa and Acinetobacter baumannii, and may be intrinsic or mediated by transferable carbapenemase-encoding genes. This type of resistance genes are already widespread in certain parts of the world, particularly Europe, Asia and South America, while the situation in other places such as sub-Saharan Africa is not well documented. In this paper, we provide an in-depth review of carbapenem resistance providing up-to-date information on the subject.
KW - Gram negative bacilli
KW - antibiotic resistance
KW - carbapenemases
KW - carbapenems
UR - http://www.scopus.com/inward/record.url?scp=85149152938&partnerID=8YFLogxK
U2 - 10.3390/medsci6010001
DO - 10.3390/medsci6010001
M3 - Review article
C2 - 29267233
AN - SCOPUS:85149152938
SN - 2076-3271
VL - 6
JO - Medical sciences (Basel, Switzerland)
JF - Medical sciences (Basel, Switzerland)
IS - 1
ER -