Carbapenem Resistance: A Review

Francis S. Codjoe, Eric S. Donkor

Research output: Contribution to journalReview articlepeer-review

461 Citations (Scopus)

Abstract

Carbapenem resistance is a major and an on-going public health problem globally. It occurs mainly among Gram-negative pathogens such as Klebsiella pneumoniae, Pseudomonas aeruginosa and Acinetobacter baumannii, and may be intrinsic or mediated by transferable carbapenemase-encoding genes. This type of resistance genes are already widespread in certain parts of the world, particularly Europe, Asia and South America, while the situation in other places such as sub-Saharan Africa is not well documented. In this paper, we provide an in-depth review of carbapenem resistance providing up-to-date information on the subject.

Original languageEnglish
JournalMedical sciences (Basel, Switzerland)
Volume6
Issue number1
DOIs
Publication statusPublished - 21 Dec 2017

Keywords

  • Gram negative bacilli
  • antibiotic resistance
  • carbapenemases
  • carbapenems

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