TY - JOUR
T1 - Bacteria and their antibiotic resistance profiles in ambient air in accra, ghana, february 2020
T2 - A cross-sectional study
AU - Azaglo, Godfred Saviour Kudjo
AU - Khogali, Mohammed
AU - Hann, Katrina
AU - Pwamang, John Alexis
AU - Appoh, Emmanuel
AU - Appah-Sampong, Ebenezer
AU - Agyarkwa, Meldon Ansah Koi
AU - Fiati, Carl
AU - Kudjawu, Jewel
AU - Hedidor, George Kwesi
AU - Akumwena, Amos
AU - Timire, Collins
AU - Tweya, Hannock
AU - Opintan, Japheth A.
AU - Harries, Anthony D.
N1 - Publisher Copyright:
© 2021 by the authors. Licensee MDPI, Basel, Switzerland.
PY - 2021/9
Y1 - 2021/9
N2 - Inappropriate use of antibiotics has led to the presence of antibiotic-resistant bacteria in ambient air. There is no published information about the presence and resistance profiles of bacteria in ambient air in Ghana. We evaluated the presence and antibiotic resistance profiles of selected bacterial, environmental and meteorological characteristics and airborne bacterial counts in 12 active air quality monitoring sites (seven roadside, two industrial and three residential) in Accra in February 2020. Roadside sites had the highest median temperature, relative humidity, wind speed and PM10 concentrations, and median airborne bacterial counts in roadside sites (115,000 CFU/m3) were higher compared with industrial (35,150 CFU/m3) and residential sites (1210 CFU/m3). Bacillus species were isolated in all samples and none were antibiotic resistant. There were, however, Pseudomonas aeruginosa, Escherichia coli, Pseudomonas species, non-hemolytic Streptococci, Coliforms and Staphylococci species, of which six (50%) showed mono-resistance or multidrug resistance to four antibiotics (penicillin, ampicillin, ciprofloxacin and ceftriaxone). There was a positive correlation between PM10 concentrations and airborne bacterial counts (rs = 0.72), but no correlations were found between PM10 concentrations and the pathogenic bacteria nor their antibiotic resistance. We call for the expansion of surveillance of ambient air to other cities of Ghana to obtain nationally representative information.
AB - Inappropriate use of antibiotics has led to the presence of antibiotic-resistant bacteria in ambient air. There is no published information about the presence and resistance profiles of bacteria in ambient air in Ghana. We evaluated the presence and antibiotic resistance profiles of selected bacterial, environmental and meteorological characteristics and airborne bacterial counts in 12 active air quality monitoring sites (seven roadside, two industrial and three residential) in Accra in February 2020. Roadside sites had the highest median temperature, relative humidity, wind speed and PM10 concentrations, and median airborne bacterial counts in roadside sites (115,000 CFU/m3) were higher compared with industrial (35,150 CFU/m3) and residential sites (1210 CFU/m3). Bacillus species were isolated in all samples and none were antibiotic resistant. There were, however, Pseudomonas aeruginosa, Escherichia coli, Pseudomonas species, non-hemolytic Streptococci, Coliforms and Staphylococci species, of which six (50%) showed mono-resistance or multidrug resistance to four antibiotics (penicillin, ampicillin, ciprofloxacin and ceftriaxone). There was a positive correlation between PM10 concentrations and airborne bacterial counts (rs = 0.72), but no correlations were found between PM10 concentrations and the pathogenic bacteria nor their antibiotic resistance. We call for the expansion of surveillance of ambient air to other cities of Ghana to obtain nationally representative information.
KW - Air pollution
KW - Ambient air
KW - Antibiotic resistance
KW - Antimicrobial (AMR) resistance surveillance
KW - Environment
KW - Ghana Environmental Protection Agency (EPA)
KW - Operational research
KW - Particulate matter
KW - Pathogenic bacteria
KW - SORT IT
UR - http://www.scopus.com/inward/record.url?scp=85109568309&partnerID=8YFLogxK
U2 - 10.3390/tropicalmed6030110
DO - 10.3390/tropicalmed6030110
M3 - Article
AN - SCOPUS:85109568309
SN - 2414-6366
VL - 6
JO - Tropical Medicine and Infectious Disease
JF - Tropical Medicine and Infectious Disease
IS - 3
M1 - 110
ER -