Antimalarial Mannoxanes: Hybrid Antimalarial Drugs with Outstanding Oral Activity Profiles and A Potential Dual Mechanism of Action

James Chadwick; Richard K. Amewu; Francesc Marti; Fatima Bousejra El Garah; Raman Sharma; Neil G. Berry; Paul A. Stocks; Hollie Burrell-Saward; Sergio Wittlin; Matthias Rottmann; Reto Brun; Donatella Taramelli; Silvia Parapini; Stephen A. Ward; Paul M. O'Neill

doi:10.1002/cmdc.201100196

Antimalarial Mannoxanes: Hybrid Antimalarial Drugs with Outstanding Oral Activity Profiles and A Potential Dual Mechanism of Action

James Chadwick
, Richard K. Amewu
, Francesc Marti
, Fatima Bousejra El Garah
, Raman Sharma
, Neil G. Berry
, Paul A. Stocks
, Hollie Burrell-Saward
, Sergio Wittlin
, Matthias Rottmann
, Reto Brun
, Donatella Taramelli
, Silvia Parapini
, Stephen A. Ward
, Paul M. O'Neill

University of Liverpool
Liverpool School of Tropical Medicine
London School of Hygiene & Tropical Medicine
Swiss Tropical and Public Health Institute Swiss TPH
University of Basel
University of Milan

Research output: Contribution to journal › Comment/debate

29 Citations (Scopus)

Original language	English
Pages (from-to)	1357-1361
Number of pages	5
Journal	ChemMedChem
Volume	6
Issue number	8
DOIs	https://doi.org/10.1002/cmdc.201100196
Publication status	Published - 1 Aug 2011
Externally published	Yes

Keywords

Antimalarial agents
Antiprotozoal agents
Hybrids
Peroxides
Tetraoxanes

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10.1002/cmdc.201100196

Cite this

Chadwick, J., Amewu, R. K., Marti, F., Garah, F. B. E., Sharma, R., Berry, N. G., Stocks, P. A., Burrell-Saward, H., Wittlin, S., Rottmann, M., Brun, R., Taramelli, D., Parapini, S., Ward, S. A., & O'Neill, P. M. (2011). Antimalarial Mannoxanes: Hybrid Antimalarial Drugs with Outstanding Oral Activity Profiles and A Potential Dual Mechanism of Action. ChemMedChem, 6(8), 1357-1361. https://doi.org/10.1002/cmdc.201100196

@article{d6691f6abdfa435b9e07c671a9b1d28c,

title = "Antimalarial Mannoxanes: Hybrid Antimalarial Drugs with Outstanding Oral Activity Profiles and A Potential Dual Mechanism of Action",

keywords = "Antimalarial agents, Antiprotozoal agents, Hybrids, Peroxides, Tetraoxanes",

author = "James Chadwick and Amewu, \{Richard K.\} and Francesc Marti and Garah, \{Fatima Bousejra El\} and Raman Sharma and Berry, \{Neil G.\} and Stocks, \{Paul A.\} and Hollie Burrell-Saward and Sergio Wittlin and Matthias Rottmann and Reto Brun and Donatella Taramelli and Silvia Parapini and Ward, \{Stephen A.\} and O'Neill, \{Paul M.\}",

year = "2011",

month = aug,

day = "1",

doi = "10.1002/cmdc.201100196",

language = "English",

volume = "6",

pages = "1357--1361",

journal = "ChemMedChem",

issn = "1860-7179",

publisher = "John Wiley and Sons Ltd",

number = "8",

}

Chadwick, J, Amewu, RK, Marti, F, Garah, FBE, Sharma, R, Berry, NG, Stocks, PA, Burrell-Saward, H, Wittlin, S, Rottmann, M, Brun, R, Taramelli, D, Parapini, S, Ward, SA & O'Neill, PM 2011, 'Antimalarial Mannoxanes: Hybrid Antimalarial Drugs with Outstanding Oral Activity Profiles and A Potential Dual Mechanism of Action', ChemMedChem, vol. 6, no. 8, pp. 1357-1361. https://doi.org/10.1002/cmdc.201100196

TY - JOUR

T1 - Antimalarial Mannoxanes

T2 - Hybrid Antimalarial Drugs with Outstanding Oral Activity Profiles and A Potential Dual Mechanism of Action

AU - Chadwick, James

AU - Amewu, Richard K.

AU - Marti, Francesc

AU - Garah, Fatima Bousejra El

AU - Sharma, Raman

AU - Berry, Neil G.

AU - Stocks, Paul A.

AU - Burrell-Saward, Hollie

AU - Wittlin, Sergio

AU - Rottmann, Matthias

AU - Brun, Reto

AU - Taramelli, Donatella

AU - Parapini, Silvia

AU - Ward, Stephen A.

AU - O'Neill, Paul M.

PY - 2011/8/1

Y1 - 2011/8/1

KW - Antimalarial agents

KW - Antiprotozoal agents

KW - Hybrids

KW - Peroxides

KW - Tetraoxanes

UR - https://www.scopus.com/pages/publications/79960683200

U2 - 10.1002/cmdc.201100196

DO - 10.1002/cmdc.201100196

M3 - Comment/debate

C2 - 21692184

AN - SCOPUS:79960683200

SN - 1860-7179

VL - 6

SP - 1357

EP - 1361

JO - ChemMedChem

JF - ChemMedChem

IS - 8

ER -

Antimalarial Mannoxanes: Hybrid Antimalarial Drugs with Outstanding Oral Activity Profiles and A Potential Dual Mechanism of Action

Keywords

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