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Alzheimer Disease Prediction: A Fusion of Clinical Health Records and Medical Imaging

  • University of Ghana
  • Ashesi University

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Research indicates that mild cognitive impairment (MCI) progresses to Alzheimer’s disease at an estimated rate of 10–15% per year. A common symptom associated with this progression is memory loss. Traditionally, studies in this field have relied on a single type of data to predict the disease's occurrence. However, recent studies have shown pro4mising results when multiple data modalities are considered. Methodologically, standard convolutional neural networks (CNNs) are typically used in successful deep learning techniques. However, they often face challenges such as large parameter sizes, resulting in computationally expensive operations. In this study, we enhance the prediction performance of Alzheimer’s disease by augmenting patient electronic health records (EHR) with magnetic resonance images (MRI), focusing on metrics like accuracy, precision, and recall. To achieve this, we utilized a stacked denoising autoencoder to generate intermediate relevant features from the patient’s EHR. Concurrently, a depthwise separable convolutional network was employed to extract features from the patient’s MRI data. Experimentally, this multimodal approach demonstrated significant improvements, recording an accuracy of 95.74%, a recall of 95.21%, and a precision of 95.00%, compared to classical CNNs used in existing networks.

Original languageEnglish
Title of host publicationNext Generation Computing and Communication Applications - First EAI International Conference, ICNGCCA 2025, Proceedings
EditorsRaghvendra Kumar, Priyadarsan Parida, Prasant Kumar Pattnaik
PublisherSpringer Science and Business Media Deutschland GmbH
Pages75-88
Number of pages14
ISBN (Print)9783032130082
DOIs
Publication statusPublished - 2026
Event1st EAI International Conference on Next Generation Computing and Communication Applications, ICNGCCA 2025 - Odisha
Duration: 18 Mar 202518 Mar 2025

Publication series

NameLecture Notes of the Institute for Computer Sciences, Social-Informatics and Telecommunications Engineering, LNICST
Volume665 LNICST
ISSN (Print)1867-8211
ISSN (Electronic)1867-822X

Conference

Conference1st EAI International Conference on Next Generation Computing and Communication Applications, ICNGCCA 2025
Country/TerritoryIndia
CityOdisha
Period18/03/2518/03/25

Keywords

  • Alzheimer's Disease
  • Convolutional Neural Network
  • Depthwise Separable Convolutional Network
  • Electronic Health Record
  • Magnetic Resonance Imaging
  • Mild Cognitive Impairment

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