TY - JOUR
T1 - A Scoping Review on Barriers to Cancer Diagnosis and Care in Low- and Middle-Income Countries
AU - Agbedinu, Kwabena
AU - Antwi, Sylvester
AU - Aduse-Poku, Livingstone
AU - Akakpo, Patrick Kafui
AU - Larrious-Lartey, Harriet
AU - Aboah, Valerie Ofori
AU - Mensah, Samuel
AU - Nyarko, Veneranda
AU - Amponsah-Manu, Forster
AU - Nsaful, Josephine
AU - Dampson, Rose
AU - Nortey, Michael
AU - Aja, Ijeoma
AU - Sheriff, Mohammed
AU - Dokurugu, Moses Abdulai
AU - Affram, Nelson
AU - Mremi, Alex
AU - Mwakyembe, Theresia
AU - Kamita, Moses
AU - Kaljee, Linda
AU - Jiagge, Evelyn
N1 - Publisher Copyright:
©2025 American Association for Cancer Research.
PY - 2025/7/1
Y1 - 2025/7/1
N2 - Cancer remains a significant global health challenge, with low- and middle-income countries (LMIC) disproportionately burdened by high mortality rates despite a lower overall incidence. Barriers to timely diagnosis and care exacerbate these disparities. This scoping review synthesizes existing literature on barriers for women in LMICs following the Joanna Briggs Institute methodology and the Preferred Reporting Items for Systematic Review and Meta-Analysis Extension for Scoping Reviews (PRISMA-ScR) guidelines. Studies on women in LMICs reporting barriers to accessing care for breast, colorectal, lung, cervix uteri, thyroid, corpus uteri, and stomach cancers were included. Twenty-nine studies involving 7,031 participants were included. The most common barriers included financial challenges (65.5%), geographic obstacles (34.5%), health system limitations (55.2%), and low health literacy (51.7%). Patients experienced significant delays, averaging 7.4 months from symptom onset to diagnosis and 4.9 months from diagnosis to treatment initiation. Structural issues such as limited diagnostic services, inadequate healthcare infrastructure, and healthcare provider shortages were widespread. Addressing the multifaceted barriers to cancer care in LMICs requires comprehensive strategies, including increasing financial support, decentralizing care services, improving healthcare infrastructure, and enhancing education for patients and providers. Policymakers and stakeholders should prioritize investments in cancer care to reduce disparities and improve outcomes. These findings will inform strategies for improving cancer care in low-resource settings globally.
AB - Cancer remains a significant global health challenge, with low- and middle-income countries (LMIC) disproportionately burdened by high mortality rates despite a lower overall incidence. Barriers to timely diagnosis and care exacerbate these disparities. This scoping review synthesizes existing literature on barriers for women in LMICs following the Joanna Briggs Institute methodology and the Preferred Reporting Items for Systematic Review and Meta-Analysis Extension for Scoping Reviews (PRISMA-ScR) guidelines. Studies on women in LMICs reporting barriers to accessing care for breast, colorectal, lung, cervix uteri, thyroid, corpus uteri, and stomach cancers were included. Twenty-nine studies involving 7,031 participants were included. The most common barriers included financial challenges (65.5%), geographic obstacles (34.5%), health system limitations (55.2%), and low health literacy (51.7%). Patients experienced significant delays, averaging 7.4 months from symptom onset to diagnosis and 4.9 months from diagnosis to treatment initiation. Structural issues such as limited diagnostic services, inadequate healthcare infrastructure, and healthcare provider shortages were widespread. Addressing the multifaceted barriers to cancer care in LMICs requires comprehensive strategies, including increasing financial support, decentralizing care services, improving healthcare infrastructure, and enhancing education for patients and providers. Policymakers and stakeholders should prioritize investments in cancer care to reduce disparities and improve outcomes. These findings will inform strategies for improving cancer care in low-resource settings globally.
UR - https://www.scopus.com/pages/publications/105009614414
U2 - 10.1158/1055-9965.EPI-25-0120
DO - 10.1158/1055-9965.EPI-25-0120
M3 - Review article
C2 - 40304503
AN - SCOPUS:105009614414
SN - 1055-9965
VL - 34
SP - 1066
EP - 1073
JO - Cancer Epidemiology Biomarkers and Prevention
JF - Cancer Epidemiology Biomarkers and Prevention
IS - 7
ER -