A Scoping Review on Barriers to Cancer Diagnosis and Care in Low- and Middle-Income Countries

  • Kwabena Agbedinu
  • , Sylvester Antwi
  • , Livingstone Aduse-Poku
  • , Patrick Kafui Akakpo
  • , Harriet Larrious-Lartey
  • , Valerie Ofori Aboah
  • , Samuel Mensah
  • , Veneranda Nyarko
  • , Forster Amponsah-Manu
  • , Josephine Nsaful
  • , Rose Dampson
  • , Michael Nortey
  • , Ijeoma Aja
  • , Mohammed Sheriff
  • , Moses Abdulai Dokurugu
  • , Nelson Affram
  • , Alex Mremi
  • , Theresia Mwakyembe
  • , Moses Kamita
  • , Linda Kaljee
  • Evelyn Jiagge

Research output: Contribution to journalReview articlepeer-review

1 Citation (Scopus)

Abstract

Cancer remains a significant global health challenge, with low- and middle-income countries (LMIC) disproportionately burdened by high mortality rates despite a lower overall incidence. Barriers to timely diagnosis and care exacerbate these disparities. This scoping review synthesizes existing literature on barriers for women in LMICs following the Joanna Briggs Institute methodology and the Preferred Reporting Items for Systematic Review and Meta-Analysis Extension for Scoping Reviews (PRISMA-ScR) guidelines. Studies on women in LMICs reporting barriers to accessing care for breast, colorectal, lung, cervix uteri, thyroid, corpus uteri, and stomach cancers were included. Twenty-nine studies involving 7,031 participants were included. The most common barriers included financial challenges (65.5%), geographic obstacles (34.5%), health system limitations (55.2%), and low health literacy (51.7%). Patients experienced significant delays, averaging 7.4 months from symptom onset to diagnosis and 4.9 months from diagnosis to treatment initiation. Structural issues such as limited diagnostic services, inadequate healthcare infrastructure, and healthcare provider shortages were widespread. Addressing the multifaceted barriers to cancer care in LMICs requires comprehensive strategies, including increasing financial support, decentralizing care services, improving healthcare infrastructure, and enhancing education for patients and providers. Policymakers and stakeholders should prioritize investments in cancer care to reduce disparities and improve outcomes. These findings will inform strategies for improving cancer care in low-resource settings globally.

Original languageEnglish
Pages (from-to)1066-1073
Number of pages8
JournalCancer Epidemiology Biomarkers and Prevention
Volume34
Issue number7
DOIs
Publication statusPublished - 1 Jul 2025

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