TY - JOUR
T1 - A review of some medicinal plants with the potential to defeat antimicrobial resistance
T2 - Cases of Benin, Togo, Ghana, Burkina Faso, and Cape Verde
AU - Dougnon, Victorien
AU - Legba, Boris Brice
AU - Gbaguidi, Bertin
AU - Agbodjento, Eric
AU - Agbankpe, Alidehou Jerrold
AU - Rocha, Diara
AU - Ayi, Irene
AU - Azonbakin, Simon
AU - Diallo, Aboudoulatif
AU - Bonkoungou, Isidore Juste
AU - Klotoe, Jean Robert
AU - Agbangla, Clément
AU - Alitonou, Guy Alain
N1 - Publisher Copyright:
© Copyright: Dougnon, et al. This article is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/ by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http:// creativecommons.org/ publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
PY - 2022
Y1 - 2022
N2 - Antimicrobial resistance (AMR) is a global public health problem. In the alternatives being explored for developing new antimicrobials, medicinal plants occupy an important place, particularly in Africa, where they are widely used. This review aims to analyze the potential of medicinal plants from Benin, Togo, Ghana, Burkina-Faso, and Cape Verde in the fight against AMR. A bibliographic search was conducted to explore scientific databases such as PubMed and Google Scholar. During this search, particular attention was given to epidemiological data related to AMR in these countries, medicinal plants traditionally used to treat microbial infections and medicinal plants that have been shown to be active on multidrug-resistant microbial strains. In total, 94 manuscripts were investigated. Epidemiological data showed that the problem of AMR is worsening in each target country. In addition, several medicinal plants have been demonstrated to be effective against microbial strains resistant to conventional antibiotics. A total of 532 medicinal plants were identified according to their ethnomedical uses for the treatment of microbial infections. Scientific evidence was collected on the antimicrobial potential of 91 plants. This study showed the potential of medicinal plants in the fight against AMR. Their documented traditional use, coupled with the evidence of efficacy provided, make them interesting sources for developing new antimicrobials.
AB - Antimicrobial resistance (AMR) is a global public health problem. In the alternatives being explored for developing new antimicrobials, medicinal plants occupy an important place, particularly in Africa, where they are widely used. This review aims to analyze the potential of medicinal plants from Benin, Togo, Ghana, Burkina-Faso, and Cape Verde in the fight against AMR. A bibliographic search was conducted to explore scientific databases such as PubMed and Google Scholar. During this search, particular attention was given to epidemiological data related to AMR in these countries, medicinal plants traditionally used to treat microbial infections and medicinal plants that have been shown to be active on multidrug-resistant microbial strains. In total, 94 manuscripts were investigated. Epidemiological data showed that the problem of AMR is worsening in each target country. In addition, several medicinal plants have been demonstrated to be effective against microbial strains resistant to conventional antibiotics. A total of 532 medicinal plants were identified according to their ethnomedical uses for the treatment of microbial infections. Scientific evidence was collected on the antimicrobial potential of 91 plants. This study showed the potential of medicinal plants in the fight against AMR. Their documented traditional use, coupled with the evidence of efficacy provided, make them interesting sources for developing new antimicrobials.
KW - Africa
KW - antimicrobial
KW - drug resistance
KW - medicinal plants
UR - http://www.scopus.com/inward/record.url?scp=85176389309&partnerID=8YFLogxK
U2 - 10.14202/IJOH.2022.124-160
DO - 10.14202/IJOH.2022.124-160
M3 - Article
AN - SCOPUS:85176389309
SN - 2455-5673
VL - 8
SP - 124
EP - 160
JO - International Journal of One Health
JF - International Journal of One Health
IS - 2
ER -