A promising microscopic technique for detecting Schistosoma mansoni eggs

M. A. Model; W. K. Anyan

doi:10.1016/j.diagmicrobio.2025.117093

A promising microscopic technique for detecting Schistosoma mansoni eggs

M. A. Model, W. K. Anyan

Department of Parasitology

Research output: Contribution to journal › Article › peer-review

Abstract

Schistosomiasis is one of the most devastating neglected tropical diseases, affecting over 250 million people worldwide and contributing to approximately 280,000 deaths annually. Microscopic detection of Schistosoma mansoni eggs in fecal samples using the Kato-Katz method remains the diagnostic standard. However, its speed and detection efficiency are limited. In this report, we present a novel microscopic technique - transmission-through-dye (TTD) imaging. TTD highlights viable eggs in bright red against a dark background, enhancing their visibility and detectability. TTD imaging appears to be a promising tool for the diagnosis of schistosomiasis.

Original language	English
Article number	117093
Journal	Diagnostic Microbiology and Infectious Disease
Volume	114
Issue number	1
DOIs	https://doi.org/10.1016/j.diagmicrobio.2025.117093
Publication status	Published - Jan 2026

Keywords

Diagnosis
Microscopy
Schistosomiasis
Transmission-though-dye (TTD)

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.diagmicrobio.2025.117093

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title = "A promising microscopic technique for detecting Schistosoma mansoni eggs",

abstract = "Schistosomiasis is one of the most devastating neglected tropical diseases, affecting over 250 million people worldwide and contributing to approximately 280,000 deaths annually. Microscopic detection of Schistosoma mansoni eggs in fecal samples using the Kato-Katz method remains the diagnostic standard. However, its speed and detection efficiency are limited. In this report, we present a novel microscopic technique - transmission-through-dye (TTD) imaging. TTD highlights viable eggs in bright red against a dark background, enhancing their visibility and detectability. TTD imaging appears to be a promising tool for the diagnosis of schistosomiasis.",

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AU - Model, M. A.

AU - Anyan, W. K.

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N2 - Schistosomiasis is one of the most devastating neglected tropical diseases, affecting over 250 million people worldwide and contributing to approximately 280,000 deaths annually. Microscopic detection of Schistosoma mansoni eggs in fecal samples using the Kato-Katz method remains the diagnostic standard. However, its speed and detection efficiency are limited. In this report, we present a novel microscopic technique - transmission-through-dye (TTD) imaging. TTD highlights viable eggs in bright red against a dark background, enhancing their visibility and detectability. TTD imaging appears to be a promising tool for the diagnosis of schistosomiasis.

AB - Schistosomiasis is one of the most devastating neglected tropical diseases, affecting over 250 million people worldwide and contributing to approximately 280,000 deaths annually. Microscopic detection of Schistosoma mansoni eggs in fecal samples using the Kato-Katz method remains the diagnostic standard. However, its speed and detection efficiency are limited. In this report, we present a novel microscopic technique - transmission-through-dye (TTD) imaging. TTD highlights viable eggs in bright red against a dark background, enhancing their visibility and detectability. TTD imaging appears to be a promising tool for the diagnosis of schistosomiasis.

KW - Diagnosis

KW - Microscopy

KW - Schistosomiasis

KW - Transmission-though-dye (TTD)

UR - https://www.scopus.com/pages/publications/105014544738

U2 - 10.1016/j.diagmicrobio.2025.117093

DO - 10.1016/j.diagmicrobio.2025.117093

M3 - Article

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SN - 0732-8893

VL - 114

JO - Diagnostic Microbiology and Infectious Disease

JF - Diagnostic Microbiology and Infectious Disease

IS - 1

M1 - 117093

ER -

A promising microscopic technique for detecting Schistosoma mansoni eggs

Abstract

Keywords

UN SDGs

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