TY - JOUR
T1 - A framework for the study of zoonotic disease emergence and its drivers
T2 - Spillover of bat pathogens as a case study
AU - Wood, James L.N.
AU - Leach, Melissa
AU - Waldman, Linda
AU - MacGregor, Hayley
AU - Fooks, Anthony R.
AU - Jones, Kate E.
AU - Restif, Olivier
AU - Dechmann, Dina
AU - Hayman, David T.S.
AU - Baker, Kate S.
AU - Peel, Alison J.
AU - Kamins, Alexandra O.
AU - Fahr, Jakob
AU - Ntiamoa-Baidu, Yaa
AU - Suu-Ire, Richard
AU - Breiman, Robert F.
AU - Epstein, Jonathan H.
AU - Field, Hume E.
AU - Cunningham, Andrew A.
PY - 2012
Y1 - 2012
N2 - Many serious emerging zoonotic infections have recently arisen from bats, including Ebola, Marburg, SARS-coronavirus, Hendra, Nipah, and a number of rabies and rabies-related viruses, consistent with the overall observation that wildlife are an important source of emerging zoonoses for the human population. Mechanisms underlying the recognized association between ecosystem health and human health remain poorly understood and responding appropriately to the ecological, social and economic conditions that facilitate disease emergence and transmission represents a substantial societal challenge. In the context of disease emergence from wildlife, wildlife and habitat should be conserved, which in turn will preserve vital ecosystem structure and function, which has broader implications for human wellbeing and environmental sustainability, while simultaneously minimizing the spillover of pathogens from wild animals into human beings. In this review, we propose a novel framework for the holistic and interdisciplinary investigation of zoonotic disease emergence and its drivers, using the spillover of bat pathogens as a case study. This study has been developed to gain a detailed interdisciplinary understanding, and it combines cutting-edge perspectives from both natural and social sciences, linked to policy impacts on public health, land use and conservation.
AB - Many serious emerging zoonotic infections have recently arisen from bats, including Ebola, Marburg, SARS-coronavirus, Hendra, Nipah, and a number of rabies and rabies-related viruses, consistent with the overall observation that wildlife are an important source of emerging zoonoses for the human population. Mechanisms underlying the recognized association between ecosystem health and human health remain poorly understood and responding appropriately to the ecological, social and economic conditions that facilitate disease emergence and transmission represents a substantial societal challenge. In the context of disease emergence from wildlife, wildlife and habitat should be conserved, which in turn will preserve vital ecosystem structure and function, which has broader implications for human wellbeing and environmental sustainability, while simultaneously minimizing the spillover of pathogens from wild animals into human beings. In this review, we propose a novel framework for the holistic and interdisciplinary investigation of zoonotic disease emergence and its drivers, using the spillover of bat pathogens as a case study. This study has been developed to gain a detailed interdisciplinary understanding, and it combines cutting-edge perspectives from both natural and social sciences, linked to policy impacts on public health, land use and conservation.
KW - Bat
KW - Collaborative framework
KW - Emergence
KW - Zoonosis
UR - http://www.scopus.com/inward/record.url?scp=84866119371&partnerID=8YFLogxK
U2 - 10.1098/rstb.2012.0228
DO - 10.1098/rstb.2012.0228
M3 - Review article
C2 - 22966143
AN - SCOPUS:84866119371
SN - 0962-8436
VL - 367
SP - 2881
EP - 2892
JO - Philosophical Transactions of the Royal Society B: Biological Sciences
JF - Philosophical Transactions of the Royal Society B: Biological Sciences
IS - 1604
ER -