A bioactive fraction from the leaves of Ceiba pentandra (L.) Gaertn. exhibits antiproliferative activity via cell cycle arrest at the G1/S checkpoint and initiation of apoptosis via poly [ADP-ribose] polymerase 1 (PARP1) cleavage in HeLa cells.

Bright Selorm Addy, Caleb Kesse Firempong, Gustav Komlaga, Patrick Addo-Fordjour, Seth Agyei Domfeh, Oluwatomisin Deborah Afolayan, Eric Nana Yaw Nyarko, Benjamin Obukowho Emikpe

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Pharmacology, Toxicology and Pharmaceutical Science