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A bioactive fraction from the leaves of Ceiba pentandra (L.) Gaertn. exhibits antiproliferative activity via cell cycle arrest at the G1/S checkpoint and initiation of apoptosis via poly [ADP-ribose] polymerase 1 (PARP1) cleavage in HeLa cells.

  • Bright Selorm Addy
  • , Caleb Kesse Firempong
  • , Gustav Komlaga
  • , Patrick Addo-Fordjour
  • , Seth Agyei Domfeh
  • , Oluwatomisin Deborah Afolayan
  • , Eric Nana Yaw Nyarko
  • , Benjamin Obukowho Emikpe
  • Kwame Nkrumah University of Science and Technology
  • Central University

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Pharmacology, Toxicology and Pharmaceutical Science